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Table 3 Eight metabolite concentrations in severe CAP and non-severe CAP patients of the validation cohort

From: Metabolic profiles in community-acquired pneumonia: developing assessment tools for disease severity

Metabolite

Concentration (ÎĽg/ml)

p value

Tendency

SCAP (n = 19)

NSCAP (n = 32)

Sphinganine

0.041 (0.028–0.050)

0.022 (0.012–0.028)

< 0.001

Controls > SCAP > NSCAP

Creatine

5.420 (3.447–8.711)

2.481 (1.739–3.767)

< 0.001

SCAP > controls > NSCAP

l-Arginine

5.043 (4.105–5.753)

5.905 (4.622–7.047)

0.016

NSCAP > SCAP > controls

Lactate

141.343

(120.670–273.794)

107.224

(86.814–137.551)

0.001

SCAP > NSCAP > controls

l-Acetylcarnitine

0.076 (0.029–0.225)

0.063 (0.042–0.098)

0.667

Controls > SCAP > NSCAP

Glycerophosphocholine

4.438 (2.596–8.170)

5.732 (3.048–7.212)

0.181

Controls > NSCAP > SCAP

DHEA-S

0.370 (0.229–0.425)

0.532 (0.379–0.812)

< 0.001

Controls > NSCAP > SCAP

p-Cresol sulfate

0.109 (0.004–0.801)

0.073 (0.012–0.203)

< 0.001

Controls > SCAP > NSCAP

  1. Data presented as median (interquartile range)
  2. CAP community-acquired pneumonia, SCAP severe CAP, NSCAP non-severe CAP, DHEA-S dehydroepiandrosterone sulfate