Skip to main content

Table 1 Consequences of ‘wrong thing–wrong time’ leading to circadian desynchronisation in critically ill patients

From: Clinical chronobiology: a timely consideration in critical care medicine

Circadian misalignment

Clinical outcome

Sleep–wake inversion

Sleep loss [113]

Delirium [114]

Poor compliance with physiotherapy and rehabilitation [115]

Continuous feeding at night time

Glucose intolerance [64]

Dyslipidaemia [72]

Metabolic dysfunction [71]

Invasive interventions at night time

Impaired wound healing [101]