Table 1 Consequences of ‘wrong thing–wrong time’ leading to circadian desynchronisation in critically ill patients
From: Clinical chronobiology: a timely consideration in critical care medicine
Circadian misalignment | Clinical outcome |
|---|---|
Sleep–wake inversion | Sleep loss [113] |
Delirium [114] | |
Poor compliance with physiotherapy and rehabilitation [115] | |
Continuous feeding at night time | Glucose intolerance [64] |
Dyslipidaemia [72] | |
Metabolic dysfunction [71] | |
Invasive interventions at night time | Impaired wound healing [101] |