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Table 1 Baseline characteristics of the study population

From: Impact of flow and temperature on patient comfort during respiratory support by high-flow nasal cannula

Characteristic

Overall population

(N = 40)

FiO2 < 45%

(N = 24)

FiO2 ≥ 45%

(N = 16)

p value, FiO2 < 45% vs FiO2 ≥ 45%

Age (years)

57 ± 15

55 ± 14

62 ± 16

0.17

Female sex, n (%)

16 (40%)

8 (33.3%)

8 (50%)

0.29

Monolateral/bilateral infiltrates, n (%)

12 (30%)/28 (70%)

8 (33%)/16 (67%)

4 (25%)/12 (75%)

0.57

SOFA score

4 (3–6)

3.5 (3–6)

4 (3–6)

0.89

Pulmonary/extrapulmonary cause of ARDS, n (%)

19 (48%)/21 (53%)

11 (46%)/13(54%)

8 (50%)/8 (50%)

0.80

Infectious/non-infectious cause of ARDS, n (%)

22 (56%)/18 (45%)

14 (58%)/10 (42%)

8 (50%)/8 (50%)

0.60

FiO2

40 (40–50)

40 (40–40)

50 (50–60)

< 0.0001*

Respiratory rate (bpm)

22 (18–24)

20 (18–24)

24 (20–30)

0.05*

Borg scale

2 (1–3)

1 (0–3)

3 (2–4)

0.02*

Comfort

4 (3–5)

4 (3–5)

4 (3–5)

0.81

SpO2/FiO2

241 (196–249)

248 (243–250)

192 (161–199)

< 0.0001*

SAPS II

36 ± 9

38 ± 8

35 ± 11

0.35

  1. Normally distributed variables reported as mean ± standard deviation, non-normal variables reported as median (interquartile range). p values obtained by t test, Wilcoxon rank-sum test, or chi-square test as appropriate
  2. ARDS acute respiratory distress syndrome, FiO 2 inspired oxygen fraction, SAPS Simplified Acute Physiology Score, SOFA Sepsis-related Organ Failure Assessment, SpO 2 peripheral oxygen saturation
  3. *Data significant at p < 0.05