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Table 3 Operational characteristics of extracorporeal carbon-dioxide removal for the 20 patients with acute respiratory distress syndrome

From: Feasibility and safety of low-flow extracorporeal CO2 removal managed with a renal replacement platform to enhance lung-protective ventilation of patients with mild-to-moderate ARDS

Characteristic Value
Blood flow (ml/min)a 421 ± 42
Time of utilization (h) 30.6 ± 21.0
Access pressure (mmHg)a − 145 ± 14
Filter pressure (mmHg)a 301 ± 19
Return pressure (mmHg)a 154 ± 21
Heparin bolus at insertion (IU) 3100 ± 1330
Heparin (IU/kg/24 h) 230 ± 78
Activated partial thromboplastin time ratio 1.8 ± 0.6
Serious adverse eventb
 Nonfatal cardiac arrest 1 (5)
Study-related adverse event
 Mild hemoptysis resolved with stopping anticoagulationc 2 (10)
 Membrane clotting 10 (50)
  Time it occurred (h) 20.0 ± 9.7
  1. Values presented as mean ± standard deviation or n (%)
  2. aRecorded in the hour following initiation of extracorporeal carbon-dioxide removal
  3. bNot device related
  4. cResolved without embolization and not related to heparin overdose