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Table 3 Operational characteristics of extracorporeal carbon-dioxide removal for the 20 patients with acute respiratory distress syndrome

From: Feasibility and safety of low-flow extracorporeal CO2 removal managed with a renal replacement platform to enhance lung-protective ventilation of patients with mild-to-moderate ARDS

Characteristic

Value

Blood flow (ml/min)a

421 ± 42

Time of utilization (h)

30.6 ± 21.0

Access pressure (mmHg)a

− 145 ± 14

Filter pressure (mmHg)a

301 ± 19

Return pressure (mmHg)a

154 ± 21

Heparin bolus at insertion (IU)

3100 ± 1330

Heparin (IU/kg/24 h)

230 ± 78

Activated partial thromboplastin time ratio

1.8 ± 0.6

Serious adverse eventb

 Nonfatal cardiac arrest

1 (5)

Study-related adverse event

 Mild hemoptysis resolved with stopping anticoagulationc

2 (10)

 Membrane clotting

10 (50)

  Time it occurred (h)

20.0 ± 9.7

  1. Values presented as mean ± standard deviation or n (%)
  2. aRecorded in the hour following initiation of extracorporeal carbon-dioxide removal
  3. bNot device related
  4. cResolved without embolization and not related to heparin overdose