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Table 3 Hemodynamic parameters

From: High-frequency oscillatory ventilation guided by transpulmonary pressure in acute respiratory syndrome: an experimental study in pigs

 

T0 PEEP 5

ARDS PEEP 5

ARDS PEEP 10

ARDS PEEP 20

HR, min− 1

Median

25%

75%

Median

25%

75%

Median

25%

75%

Median

25%

75%

 VCV

55.7

50.2

59.9

57.6

49.7

60.4

49.3#^

44.6

53.9

67.6

63.6

84.2

 ARDS HFOV con

–

–

–

–

–

–

60.0

48.5

63.8

75.2

66.1

79.5

 ARDS HFOV PL mean

–

–

–

–

–

–

56.7

43.9

60.5

72.5

54.4

77.4

MAP, mmHg

 VCV

82.9

76.2

89.2

71.8

65.4

86.7

54.6#♀

50.9

57.7

59.7©£

52.5

62.3

 ARDS HFOV con

–

–

–

–

–

–

65.9

57.3

74.6

59.4 Ω

54.4

62.8

 ARDS HFOV PL mean

–

–

–

–

–

–

68.9

62.2

70.7

66.3

64.6

70.8

CVP, mmHg

 VCV

12.5

11.0

14.5

11.5

8.5

12.3

7.0#^♀

6.0

9.5

10.0

7.8

11.5

 ARDS HFOV con

–

–

–

–

–

–

9.5

7.8

10.5

10.5

9.0

12.3

 ARDS HFOV PL mean

–

–

–

–

–

–

8.0

7.0

10.5

10.0

8.0

12.3

mPAP, mmHg

 VCV

19.3*

17.6

21.3

25.4

23.3

28.1

22.1#

18.7

25.1

26.6

21.8

27.7

 ARDS HFOV con

–

–

–

–

–

–

21.9

19.1

31.3

25.6

21.2

31.4

 ARDS HFOV PL mean

–

–

–

–

–

–

21.2

17.1

26.1

24.0

21.7

26.7

CO, l.min−1

 VCV

2.2

2.1

2.5

2.6

2.4

3.1

2.4

2.2

2.6

2.4©

2.1

2.6

 ARDS HFOV con

–

–

–

–

–

–

2.5

2.3

2.8

2.1 Ω

1.8

2.5

 ARDS HFOV PL mean

–

–

–

–

–

–

2.4

2.2

3.0

2.5

2.2

2.9

SV, ml

 VCV

46.4

41.1

63.9

45.7

38.2

55.2

48.1#

45.0

55.3

28.3©

25.5

39.9

 ARDS HFOV con

–

–

–

–

–

–

46.5⃝

38.0

58.4

26.1 Ω

18.9

37.2

 ARDS HFOV PL mean

–

–

–

–

–

–

53.4

42.2

59.0

36.4

20.9

54.2

RVEDI, ml m−2

 VCV

90.3*

86.2

97.5

104.0

97.7

127.6

103.9

96.1

110.5

102.2

90.6

120.6

 ARDS HFOV con

–

–

–

–

–

–

102.8

101.1

115.9

86.6

71.3

101.3

 ARDS HFOV PL mean

–

–

–

–

–

–

119.5

99.3

133.6

98.5

94.1

100.4

ITBI; ml m2

 VCV

550.0

514.4

603.1

637.2

586.5

718.8

638.5

604.8

708.9

575.8©£

513.5

651.8

 ARDS HFOV con

–

–

–

–

–

–

651.7

611.3

706.1

560.7 Ω

506.8

665.9

 ARDS HFOV PL mean

–

–

–

–

–

–

660.6

639.6

733.0

621.0

573.0

675.7

ELWI, ml kg−1

 VCV

4.9*

4.6

5.0

10.6

9.9

12.4

14.0#^

12.8

15.3

16.2

14.5

19.1

 ARDS HFOV con

–

–

–

–

–

–

15.2

14.3

17.0

16.5

15.9

20.3

 ARDS HFOV PL mean

–

–

–

–

–

–

15.0

14.1

16.1

16.3

15.7

20.5

  1. Values are medians (25th and 75th quartiles) in eight animals. See text or Table 1 for description of groups
  2. HR heart rate, MAP mean arterial pressure, CVP central venous pressure, mPAP mean pulmonary artery pressure, PCWP pulmonary capillary wedge pressure, CO cardiac output, SV stroke volume, SVV stroke volume variation, ITBI intrathoracic blood volume index, ELWI extravascular lung water index, ARDS acute respiratory distress syndrome, PEEP positive end-expiratory pressure
  3. *p < 0.05 VCV T0 PEEP 5 vs. VCV ARDS PEEP 5; #p < 0.05 VCV ARDS PEEP 10 vs. VCV ARDS PEEP 20; ^p < 0.05 VCV ARDS PEEP 10 vs. HFOV con “PEEP 10”; ♀p < 0.05 VCV ARDS PEEP 10 vs. HFOV PL mean “PEEP 10”; ⃝p < 0.05 HFOV con ARDS “PEEP 10” vs. HFOV PL mean ARDS “PEEP 10”; ©p < 0.05 VCV ARDS PEEP 20 vs. HFOV con “PEEP 20”; £p < 0.05 VCV ARDS PEEP 20 vs. HFOV PL mean “PEEP 20”; Ωp < 0.05 HFOV con ARDS “PEEP 20” vs. HFOV PL mean ARDS “PEEP 20”; p < 0.05 (p values were determined using the Wilcoxon test for paired samples)
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Critical Care

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