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Table 3 Hemodynamic parameters

From: High-frequency oscillatory ventilation guided by transpulmonary pressure in acute respiratory syndrome: an experimental study in pigs

  T0 PEEP 5 ARDS PEEP 5 ARDS PEEP 10 ARDS PEEP 20
HR, min− 1 Median 25% 75% Median 25% 75% Median 25% 75% Median 25% 75%
 VCV 55.7 50.2 59.9 57.6 49.7 60.4 49.3#^ 44.6 53.9 67.6 63.6 84.2
 ARDS HFOV con 60.0 48.5 63.8 75.2 66.1 79.5
 ARDS HFOV PL mean 56.7 43.9 60.5 72.5 54.4 77.4
MAP, mmHg
 VCV 82.9 76.2 89.2 71.8 65.4 86.7 54.6#♀ 50.9 57.7 59.7©£ 52.5 62.3
 ARDS HFOV con 65.9 57.3 74.6 59.4 Ω 54.4 62.8
 ARDS HFOV PL mean 68.9 62.2 70.7 66.3 64.6 70.8
CVP, mmHg
 VCV 12.5 11.0 14.5 11.5 8.5 12.3 7.0#^ 6.0 9.5 10.0 7.8 11.5
 ARDS HFOV con 9.5 7.8 10.5 10.5 9.0 12.3
 ARDS HFOV PL mean 8.0 7.0 10.5 10.0 8.0 12.3
mPAP, mmHg
 VCV 19.3* 17.6 21.3 25.4 23.3 28.1 22.1# 18.7 25.1 26.6 21.8 27.7
 ARDS HFOV con 21.9 19.1 31.3 25.6 21.2 31.4
 ARDS HFOV PL mean 21.2 17.1 26.1 24.0 21.7 26.7
CO, l.min−1
 VCV 2.2 2.1 2.5 2.6 2.4 3.1 2.4 2.2 2.6 2.4© 2.1 2.6
 ARDS HFOV con 2.5 2.3 2.8 2.1 Ω 1.8 2.5
 ARDS HFOV PL mean 2.4 2.2 3.0 2.5 2.2 2.9
SV, ml
 VCV 46.4 41.1 63.9 45.7 38.2 55.2 48.1# 45.0 55.3 28.3© 25.5 39.9
 ARDS HFOV con 46.5 38.0 58.4 26.1 Ω 18.9 37.2
 ARDS HFOV PL mean 53.4 42.2 59.0 36.4 20.9 54.2
RVEDI, ml m−2
 VCV 90.3* 86.2 97.5 104.0 97.7 127.6 103.9 96.1 110.5 102.2 90.6 120.6
 ARDS HFOV con 102.8 101.1 115.9 86.6 71.3 101.3
 ARDS HFOV PL mean 119.5 99.3 133.6 98.5 94.1 100.4
ITBI; ml m2
 VCV 550.0 514.4 603.1 637.2 586.5 718.8 638.5 604.8 708.9 575.8©£ 513.5 651.8
 ARDS HFOV con 651.7 611.3 706.1 560.7 Ω 506.8 665.9
 ARDS HFOV PL mean 660.6 639.6 733.0 621.0 573.0 675.7
ELWI, ml kg−1
 VCV 4.9* 4.6 5.0 10.6 9.9 12.4 14.0#^ 12.8 15.3 16.2 14.5 19.1
 ARDS HFOV con 15.2 14.3 17.0 16.5 15.9 20.3
 ARDS HFOV PL mean 15.0 14.1 16.1 16.3 15.7 20.5
  1. Values are medians (25th and 75th quartiles) in eight animals. See text or Table 1 for description of groups
  2. HR heart rate, MAP mean arterial pressure, CVP central venous pressure, mPAP mean pulmonary artery pressure, PCWP pulmonary capillary wedge pressure, CO cardiac output, SV stroke volume, SVV stroke volume variation, ITBI intrathoracic blood volume index, ELWI extravascular lung water index, ARDS acute respiratory distress syndrome, PEEP positive end-expiratory pressure
  3. *p < 0.05 VCV T0 PEEP 5 vs. VCV ARDS PEEP 5; #p < 0.05 VCV ARDS PEEP 10 vs. VCV ARDS PEEP 20; ^p < 0.05 VCV ARDS PEEP 10 vs. HFOV con “PEEP 10”; p < 0.05 VCV ARDS PEEP 10 vs. HFOV PL mean “PEEP 10”; p < 0.05 HFOV con ARDS “PEEP 10” vs. HFOV PL mean ARDS “PEEP 10”; ©p < 0.05 VCV ARDS PEEP 20 vs. HFOV con “PEEP 20”; £p < 0.05 VCV ARDS PEEP 20 vs. HFOV PL mean “PEEP 20”; Ωp < 0.05 HFOV con ARDS “PEEP 20” vs. HFOV PL mean ARDS “PEEP 20”; p < 0.05 (p values were determined using the Wilcoxon test for paired samples)