T0 PEEP 5 | ARDS PEEP 5 | ARDS PEEP 10 | ARDS PEEP 20 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
pHa | Median | 25% | 75% | Median | 25% | 75% | Median | 25% | 75% | Median | 25% | 75% |
VCV | 7.47 | 7.46 | 7.50 | 7.36 | 7.35 | 7.39 | 7.34^ | 7.32 | 7.42 | 7.31 | 7.28 | 7.34 |
ARDS HFOV con | – | – | – | – | – | – | 7.54 | 7.49 | 7.58 | 7.51 | 7.47 | 7.52 |
ARDS HFOV PL mean | – | – | – | – | – | – | 7.46 | 7.36 | 7.52 | 7.58 | 7.51 | 7.59 |
PaCO2, mmHg | ||||||||||||
VCV | 41.5 | 38.3 | 42.8 | 45.0# | 43.0 | 46.5 | 50.5^ | 46.3 | 52.0 | 51.0© | 48.3 | 55.3 |
ARDS HFOV con | – | – | – | – | – | – | 28.0 ⃝ | 27.0 | 30.3 | 29.5 | 27.0 | 33.3 |
ARDS HFOV PL mean | – | – | – | – | – | – | 40.5 | 32.8 | 47.5 | 28.0 | 25 | 29.3 |
PaO2, mmHg | ||||||||||||
VCV | 666.0* | 647.8 | 675.8 | 71.0 | 65.3 | 80.8 | 54.0 | 50.8 | 71.8 | 88.0 | 46.0 | 121.8 |
ARDS HFOV con | – | – | – | – | – | – | 51.0 | 39.8 | 71.8 | 67.5 | 39.0 | 105.8 |
ARDS HFOV PL mean | – | – | – | – | – | – | 43.5 | 40.5 | 52.8 | 63.0 | 53.0 | 131.1 |
Lactate, mmol/l | ||||||||||||
VCV | 1.9* | 1.5 | 2.4 | 2.4 | 1.6 | 3.1 | 2.4 | 2.0 | 2.8 | 2.8 | 2.4 | 3.3 |
ARDS HFOV con | – | – | – | – | – | – | 2.7 | 2.5 | 3.2 | 2.6 | 2.5 | 3.0 |
ARDS HFOV PL mean | – | – | – | – | – | – | 2.6 | 2.1 | 3.0 | 2.8 | 2.6 | 3.4 |
Airway pressures | ||||||||||||
Plateau airway pressure VCV | 14.5 | 14.0 | 16.0 | 24.5 | 23.8 | 26.0 | 29.5 | 28.0 | 30.3 | 38.5 | 37.8 | 39.0 |
Mean air pressure | ||||||||||||
VCV | 8.0 | 8.0 | 8.7 | 11.5 | 11.3 | 12.0 | 16.5 | 16.0 | 16.8 | 26.1 | 25.9 | 26.3 |
HFOV con | – | – | – | – | – | – | 20.5 | 19.5 | 21.0 | 30.0 | 30.0 | 30.0 |
HFOV PL mean | – | – | – | – | – | – | 11.0 | 11.0 | 16.3 | 20.5 | 17.0 | 22.8 |
Mean esophageal pressure | ||||||||||||
VCV | 4.5 | 1.2 | 8.4 | 4.5 | 3.7 | 9.2 | 10.0 | 7.1 | 12.3 | 12.2 | 10.2 | 14.3 |
HFOV con | – | – | – | – | – | – | 10.0 | 7.1 | 12.3 | 11.5 | 9.3 | 14.3 |
HFOV PL mean | – | – | – | – | – | – | 8.5 | 7.0 | 9.3 | 9.0 | 7.0 | 11.5 |
PL mean | ||||||||||||
VCV | 3.8 | 0.0 | 6.8 | 6.7 | 3.4 | 7.3 | 6.3 | 4.1 | 9.7 | 13.5 | 11.9 | 15.5 |
HFOV con | – | – | – | – | – | – | 9.5 | 6.5 | 13.3 | 18.5 | 15.8 | 20.8 |
HFOV PL mean | – | – | – | – | – | – | 3.0 | 1.5 | 9.0 | 11.5 | 7.8 | 15.8 |