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Table 2 Associations between Th17, Th1, and Th2 cytokine scores early after infection and death during first 90 days after Staphylococcus aureus bacteremia

From: Distinct T-helper cell responses to Staphylococcus aureus bacteremia reflect immunologic comorbidities and correlate with mortality

 

Associations between each variable and death during the first 90 days after infection

Multivariable model of Th17 and Th1 scores

Multivariable model of Th17 and Th2 scores

Multivariable model of Th1 and Th2 scores

HR

95% CI

p Value

HR

95% CI

p Value

HR

95% CI

p Value

HR

95% CI

p Value

Th17 score at time point 1

1.05

0.99–1.10

0.14

1.18

1.06–1.31

0.003

1.21

1.04–1.41

0.01

–

–

–

Th1 score at time point 1

0.98

0.89–1.08

0.66

0.81

0.68–0.96

0.02

–

–

–

0.88

0.73–1.06

0.17

Th2 score at time point 1

1.01

0.96–1.07

0.66

–

–

–

0.86

0.74–1.00

0.049

1.09

0.97–1.22

0.16

  1. Associations between each helper T-cell (Th) score and death was determined using a Cox proportional hazards model. Three multivariable Cox proportional hazards models were performed, each including two of the three helper T cell scores as predictor variables. Dashes signify variables that were not included in the model