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Table 4 Fractional target attainment (FTA) for micafungin

From: Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients

 

100 mg/24 h

150 mg/24 h

200 mg/24 h

Body weight (kg)

45

80

115

150

185

45

80

115

150

185

45

80

115

150

185

C. albicans

74.6

62.6

56.6

46.4

37.4

97.0

95.9

90.6

82.6

80.6

99.1

99.0

98.9

98.6

98.0

C. glabrata

62.0

52.3

47.5

39.3

32.2

86.4

82.6

76.5

69.3

67.0

94.2

91.7

90.4

88.1

85.8

C. tropicalis

23.9

19.3

17.1

15.9

11.0

49.6

40.8

34.1

28.8

26.1

67.9

60.8

57.3

51.4

46.1

C. parapsilosis

1.6

1.2

1.0

0.9

0.9

3.6

2.7

2.4

2.2

1.9

6.6

4.6

3.7

3.3

3.0

  1. Micafungin FTA calculated using MIC distributions [20] for the different Candida species