Table 2 Patient characteristics and mortality ratio stratified according to sepsis severity
From: Epidemiology of sepsis in intensive care units in Turkey: a multicenter, point-prevalence study
All infected patients n = 863 | Infection n = 237 | Infection + SIRS n = 163 | Severe sepsis without shock n = 260 | Septic shock (SEPSIS I) n = 203 | Septic shocka(SEPSIS-III) n = 104 | |
|---|---|---|---|---|---|---|
Age, yrs | 69 (55–79) | 70 (58–80) | 64 (52–78) | 69 (50–78) | 70 (58–79)* | 67 (57–76) |
Female/male, n | 366/497 | 104/133 | 68/95 | 108/152 | 86/117 | 46/58 |
APACHE II score at ICU admissionb | 21 (16–28) | 20 (15–24) | 18.0 (15–24) | 21.5 (17–28)‡ | 25(19–31)c | 25.5(19.7-31.2) |
SOFA score b | 7 (5–11) | 6 (4–9) | 5 (3–8) | 8 (6–11)ƒ | 10 (7–13)ƒ, † | 11 (8–14) |
Comorbidities, n (%) | ||||||
Chronic respiratory disease | 192 (22.3) | 52 (21.9) | 39 (23.9) | 57 (21.9) | 44 (21.7) | 24 (23.0) |
Cerebrovascular accident | 118 (13.6) | 34 (14.3) | 29 (17.7) | 36 (13.8) | 19 (9.4) | 12 (11.5) |
Congestive heart failure | 98 (11.3) | 21 (8.4) | 18 (10.4) | 0 (10.0) | 29 (17.2) | 18 (17.3) |
Chronic renal failure | 95 (11) | 23 (9.7) | 18 (11) | 28 (10.7) | 26 (12.8) | 14 (13.5) |
Solid organ malignancy | 81 (9.3) | 17 (7.1) | 14 (8.5) | 24 (9.2) | 26 (12.8) | 15 (14.4) |
Immunosuppression | 67 (7.7) | 9 (3.8) | 10 (6.1) | 22 (8.4)Ø | 26 (12.8)# | 21 (20.1) |
Liver disease | 22 (2.5) | 5 (2.1) | 1 (0.6) | 7 (2.6) | 9 (4.4) | 7 (6.7) |
Alcoholism | 17 (1.9) | 6 (2.5) | 3 (1.8) | 3 (1.2) | 5 (2.5) | 2 (1.9) |
Number of acute organ dysfunctions (mean ± SD) | – | – | 2.0 ± 1.0 | 3.7 ± 1.5& | 4.4 ± 1.3 | |
Organ dysfunction, n (%) | ||||||
Respiratory | 271 (31.4) | – | – | 147 (56.5) | 124 (61.1) | 74 (71.2) |
Renal | 223 (25.8) | – | – | 104 (40.0) | 119 (58.6)& | 70 (67.3) |
Neurologic | 171 (19.8) | – | – | 70 (26.9) | 101 (49.8)& | 56 (53.8) |
Liver | 133 (15.4) | – | – | 70 (26.9) | 63 (31.0) | 38 (36.5) |
Hematologic | 118 (13.6) | – | – | 64 (24.6) | 54 (26.6) | 36 (34.6) |
Lactic acidosis (> 2 mmol∙L−1), n (%) | 174 (20.2) | – | – | 83 (31.9) | 91 (44.8)€ | 104 (100) |
Therapies, n (%) | ||||||
RRT | 152 (17.6) | 21 (8.9) | 22 (13.5) | 53 (21.5) | 56 (26.1) | 28 (26.9) |
MV | 715 (82.9) | 176 (74.3) | 123 (75.5) | 227 (87.3) | 189 (93.1) | 94 (90.4) |
Length of stay, daye | 27 (13–45) | 30 (13–47) | 27 (13–48) | 30(14.2–45.7) | 22 (11.2-36.5)¢ | 17 (10–30) |
Mortality, n (%) | 401 (46.1) | 61 (24.8) | 52 (31.2) | 145 (55.7)ƒ | 143 (70.4)ƒ, † | 79 (75.9) |