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Table 4 Initial treatment efficacy and long-term therapeutic data in ICU

From: Diagnostic and management of life-threatening Adult-Onset Still Disease: a French nationwide multicenter study and systematic literature review

  Initial treatment efficacy
Literature (n = 79) Present series (n = 20) Pooled
Treatment n Efficacy n Efficacy Efficacy
Corticosteroids alone 75 51 (68%) 20 10 (50%) 61/95 (64%)
IVIg 21 10 (48%)a 6 1 (17%) 11/27 (41%)
Cyclosporine 15 12 (80%) 3 1 (33%) 13/18 (72%)
Anakinra (IL1Ra) 4 4 (100%) 5 4 (80%) 8/9 (89%)
Etoposide 0 0 (0%) 3 2 (67%) 2/3 (67%)
  1. ICU intensive care unit, IL1Ra interleukin1 receptor antagonist, IVIg intravenous immunoglobulins, aEfficacy of IVIg monotherapy = 5/9 (55.6%)