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Table 4 Initial treatment efficacy and long-term therapeutic data in ICU

From: Diagnostic and management of life-threatening Adult-Onset Still Disease: a French nationwide multicenter study and systematic literature review

 

Initial treatment efficacy

Literature (n = 79)

Present series (n = 20)

Pooled

Treatment

n

Efficacy

n

Efficacy

Efficacy

Corticosteroids alone

75

51 (68%)

20

10 (50%)

61/95 (64%)

IVIg

21

10 (48%)a

6

1 (17%)

11/27 (41%)

Cyclosporine

15

12 (80%)

3

1 (33%)

13/18 (72%)

Anakinra (IL1Ra)

4

4 (100%)

5

4 (80%)

8/9 (89%)

Etoposide

0

0 (0%)

3

2 (67%)

2/3 (67%)

  1. ICU intensive care unit, IL1Ra interleukin1 receptor antagonist, IVIg intravenous immunoglobulins, aEfficacy of IVIg monotherapy = 5/9 (55.6%)
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Critical Care

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