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Fig. 5 | Critical Care

Fig. 5

From: Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?

Fig. 5

Gene expression of messenger RNA (mRNA) related to oxidative stress in the comparison between patients with sepsis (enrollment and 7 days later) versus healthy control subjects. * Unadjusted p value < 0.001; adjusted p value = 0.003. # Unadjusted p value < 0.001; adjusted p value = 0.008. $ Unadjusted p value = 0.001; adjusted p value = 0.03. @ Unadjusted p value = 0.004; adjusted p value = 0.04. Unadjusted p value = 0.005; adjusted p value = 0.04. § Unadjusted p value < 0.001; adjusted p value = 0.01. Ψ Unadjusted p value = 0.007; adjusted p value = 0.05. Unadjusted p value refers to Wilcoxon test. Adjusted p value refers to Benjamini-Hochberg correction for multiple comparisons. n = 21 for sepsis D0; n = 16 for sepsis D7; and n = 10 for controls. MPO Myeloperoxidase, FOXM1 Forkhead box protein M1, SELS Selenoprotein S, GLRX2 Glutaredoxin 2, PRDX3 Peroxiredoxin 3, SOD2 Superoxide dismutase 2

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Critical Care

ISSN: 1364-8535