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Table 1 Characteristics of patients at baseline

From: Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis

Variable Visceral to subcutaneous adipose tissue ratio (VAT/SAT)
< median (n = 36) ≥ median (n = 37) p value
Baseline characteristics
 Age, (IQR) 38–70 56–68 0.025
 Male, n (%) 18 (50.0) 35 (94.6) <0.001
 Caucasians, n (%) 31 (93.9)a 20 (80.0) 0.145
Chronic condition, n (%)
 Hypertension 14 (38.9) 12 (32.4) 0.740
 Congestive heart failure 4 (11.1) 3 (8.1) 0.711
 Myocardial infarction 3 (8.3) 3 (8.1) 0.136
 Diabetes mellitus 9 (25.0) 10 (27.0) 1.000
 COPD 5 (13.9) 11 (29.7) 0.176
 Chronic kidney disease 2 (5.6) 6 (16.2) 0.261
 Cirrhosis 1 (2.8) 4 (10.8) 0.358
 Malignancy 2 (5.6) 2 (5.4) 1.000
Hemodynamic variables at admission (IQR)
 Mean arterial pressure 66–89 72–84 0.911
 Heart rate 83–104 79–115 0.704
 Respiratory rateb 16–20 17–22 0.323
 Temperature (°C) 36.4–37.2 36.3–37.1 0.661
Laboratory measurements at admission (IQR)
 Hemoglobin (g/L) 88.0–130.0 87.0–127.0 0.467
 WBC (×103/mm3) 5.90–12.97 6.67–17.65 0.220
 Platelets (109/L) 128–362 119–230 0.075
 Creatinine (mmol/L) 64–119 77–180 0.039
 Lactate (mmol/L) 1.1–1.9 1.3–3.3 0.179
Other clinical characteristics
 APACHE II score (IQR) 3–12 8–17 0.028
 Use of vasopressor, n (%) 6 (16.7) 6 (16.2) 0.871
 Mechanical ventilation, n (%) 12 (33.3) 14 (37.8) 0.444
PCSK9 genotype, n (%)
 One or more loss-of-function 20 (55.6) 15 (40.5) 0.294
 Two or more loss-of-function 5 (13.9) 9 (24.3) 0.404
 Adipose tissue area (cm2) (IQR)
 Visceral adipose tissue 44.7–138.5 126.8–279.5 <0.001
 Subcutaneous adipose tissue 116.5–270.8 99.8–212.2 0.300
  1. Abbreviations: VAT visceral abdominal tissue, SAT subcutaneous adipose tissue, IQR interquartile range, COPD chronic obstructive pulmonary disease, WBC white blood cell, APACHE II acute physiology and chronic health evaluation II
  2. aMissing data, n = 3
  3. bBreaths per minute