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Table 1 Individual patient parameters, flexible bronchoscopy performance, and outcomes (n = 7)

From: Feasibility, safety, and utility of bronchoscopy in patients with ARDS while in the prone position

Variable

Patient 1

Patient 2

Patient 3

Patient 4

Patient 5

Patient 6

Patient 7

Age (years)

63

18

44

79

53

23

61

Sex

Female

Female

Male

Male

Male

Female

Male

Ethnicity

Black

Caucasian

Caucasian

Asian

Caucasian

Black

Caucasian

Etiology of ARDS

MRSA sepsis

Massive pulmonary embolism

Fulminant hepatic failure, Klebsiella sepsis

Pneumonia

Massive aspiration

Massive aspiration

Pneumonia

Total ICU LOS (days)/day of FB

27/9

30/13

97/32

35/29

9/2

49/11

16/1

Prone-positioning protocol (total hours)

28

18

16

236

20

133

18

30-day survival post ICU discharge

No

Yes

Yes

No

Yes

Yes

No

Ventilator-related parameters at FBa

 Mode

PRVC

PC/AC

VC/AC

PRVC

VC/AC

PC/AC

PC/AC

 Peak pressure (cmH2O)

32

29

24

37

30

20

32

 Plateau pressure (cmH2O)

27

NA

NA

30

26

NA

27

 PEEP (cmH2O)

11

12

15

8

10

10

14

 FIO2 (%)

100

100

100

100

100

100

100

FB-related data

 Δ-diameter ETT to bronchoscope (mm)

1.7

2.0

1.7

2.0

2.0

4.0

3.1

 Therapeutic aspiration

Yes

Yes

Yes

No

Yes

Yes

Yes

 Bronchial washings / BAL

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Monitoring data

 MAP

  Baselinea

69

67

87

68

72

67

80

  Trough during FB

69

64

72

66

71

67

68

 SpO2

  Baselinea

94

98

97

100

100

100

100

  Trough during FB

94

92

97

87

99

99

100

 EtCO2

  Baselinea

48

30

NA

43

NA

NA

NA

  Trough during FB

49

30

NA

51

NA

NA

NA

Change in antibiotic regimen based on culture results

De-escalation

De-escalation

No

Additional coverage

De-escalation

De-escalation

De-escalation

  1. ARDS adult respiratory distress syndrome, ICU intensive care unit, LOS length of stay, FB flexible bronchoscopy, MRSA methicillin-resistant Staphylococcus aureus, PRVC pressure-regulated volume control, PC/AC pressure-cycled assist-controlled, VC/AC volume-cycled assist-controlled, PEEP positive end-expiratory pressure, ETT endotracheal tube, BAL bronchoalveolar lavage, MAP mean arterial pressure as measured with an arterial line, NA not available, SpO 2 oxygen saturation as measured with pulse oximetry, EtCO 2 end-tidal carbon dioxide,FIO 2 fractional concentration of inspired oxygen
  2. aAs documented prior to first bronchoscope insertion