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Table 4 Cox proportional hazards regression analysis of the effects of multiple variables on 30-day survival

From: Serum suPAR and syndecan-4 levels predict severity of community-acquired pneumonia: a prospective, multi-centre study

VariablesUnivariate analysisMultivariate analysis
HR (95% CI)p valueHR (95% CI)p value
Age (>71 years)3.709 (1.463‒9.405)0.006  
WBC (>16.40×109/L)2.560 (0.956‒6.858)0.062  
NLR (>15.77)2.282 (0.904‒5.759)0.081  
PCT (>0.34 μg/L)4.069 (0.901‒18.380)0.068  
CURB-65 (>1)2.607 (0.977‒6.960)0.056  
PSI (>113)5.998 (1.967‒18.286)0.002  
APACHE II (>14)6.177 (1.781‒21.419)0.004  
suPAR (≥10.22 ng/mL)7.724 (2.887‒20.663)<0.0018.850 (2.716‒28.831)<0.001
Syndecan-4 (≤6.68 ng/mL)5.792 (1.901‒17.641)0.0023.976 (1.217‒12.989)0.022
  1. HR hazard ratio, WBC whole blood leukocyte count, NLR neutrophil/lymphocyte ratio, PCT procalcitonin, CURB-65 confusion, urea, respiratory rate, blood pressure, and age ≥65 years old score, PSI Pneumonia Severity Index score, APACHE II Acute Physiology and Chronic Health Evaluation II score, suPAR soluble urokinase-type plasminogen activator receptor