Table 3 Fractional target attainment (FTA) for directed therapy for susceptible P. aeruginosa (MIC < 2 mg/L, 45,715 isolates)
RD [mL/d] | Dose (40% f T > MIC) | Dose (100% f T > MIC) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
0.5 g q12 | 0.5 g q8 | 1 g q12 | 1 g q8 | 2 g q8 | 0.5 g q12 | 0.5 g q8 | 1 g q12 | 1 g q8 | 2 g q8 | |
0 | 99.9 | 99.9 | 100 | 100 | 100 | 94.0 | 99.3 | 99.7 | 99.9 | 100 |
100 | 99.7 | 99.9 | 99.9 | 100 | 100 | 91.3 | 97.5 | 97.5 | 99.6 | 99.9 |
300 | 97.8 | 99.6 | 99.7 | 99.9 | 100 | 67.8 | 86.3 | 81.8 | 86.6 | 97.0 |