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Table 2 Measurement frequencies for International Microdialysis Forum Tier 1 substances, by treatment phase

From: Cerebral metabolic effects of strict versus conventional glycaemic targets following severe traumatic brain injury

 

Group

Normala

Stricta

Total

P valueb

Glucose (mmol/L)

> 0.8

110 (6)

78 (42)

188 (50)

0.22

0.2–0.8

79 (41)

102 (54)

181 (48)

< 0.2

2 (1)

8 (4)

10 (3)

  

191

188

379

 

Lactate/pyruvate ratio

< 25

83 (42)

116 (60)

199 (51)

0.32

25–40

101 (52)

67 (35)

168 (43)

> 40

12 (6)

9 (5)

21 (5)

  

196

192

388

 

Lactate (mmol/L)

< 4

142 (73)

156 (81)

298 (77)

0.69

≥ 4

54 (28)

36 (19)

90 (23)

  

196

192

388

 
  1. a Cells are shown as number (percent) for single measurements
  2. b Probability of group effect between treatment phases by chi-square test for generalised estimating equation estimates, using a binomial distribution and logit link, clustered by patient