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Table 2 Lung mechanics, gas exchange, and hemodynamics data

From: Variation of poorly ventilated lung units (silent spaces) measured by electrical impedance tomography to dynamically assess recruitment

Variable PEEP 5 incremental phase PEEP 10 incremental phase PEEP 15 PEEP 10 decremental phase PEEP 5 decremental phase Friedman test p value
VT, ml/kg IBW 7.4 [7.0–7.8] 7.5 [7.2–7.8] 7.6 [7.4–7.8] 7.6 [7.4–7.8] 7.6 [7.4–7.8] 0.171
RR, breaths/minute 15 [14–16] 16 [15–18] 16 [14–18] 16 [14–18] 15 [14–18] 0.275
MV, L/minute 6.4 [5.8–6.6] 6.9 [6.4–7.7] 6.8 [6.5–8.0] 6.8 [6.5–8.4] 6.8 [6.4–7.8] 0.222
Ppeak, cmH2O 21 [19–28] 28 [26–30]a 34 [32–35]a,b 27 [25–30]a,c 23 [21–28]b,c,d <0.001
Pplat, cmH2O 15 [14–19] 21 [20–23]a 26 [25–27]a,b 20 [18–22]a,b,c 15 [13–20]b,c,d < 0.001
Driving pressure, cmH2O 10 [10–15] 11 [10–13] 12 [10–12] 10 [8–12] 10 [8–15] 0.100
Crs, ml/cmH2O 39 [32–47] 38 [34–44] 38 [34–43] 43 [35–57] 45 [30–52] 0.100
PaCO2, mmHg 53.8 [49.1–59.0] 53.3 [49.2–58.0] 54.0 [50.4–59.7] 52.2 [47.1–56.1] 51.8 [44.7–57.5] 0.246
PaO2/FiO2, mmHg 233 [159–286] 234 [163–279] 255 [178–292] 253 [203–320] 246 [172–304] 0.611
pH 7.33 [7.30–7.39] 7.34 [7.30–7.41] 7.32 [7.29–7.40] 7.34 [7.29–7.38] 7.34 [7.31–7.39] 0.170
MAP, mmHg 70 [66–85] 76 [67–83] 71 [64–76] 74 [66–80] 78 [70–82] 0.490
HR, beats/minute 76 [72–86] 76 [68–84]a 72 [67–84]a 73 [64–83]a 77 [63–85] 0.021
  1. Abbreviations: PEEP Positive end-expiratory pressure, RM Recruitment maneuver, V T Tidal volume, IBW Ideal body weight, RR Respiratory rate, MV Minute ventilation, Ppeak Peak airway pressure, Pplat Plateau airway pressure, Crs Respiratory system compliance, PaCO 2 Partial pressure of carbon dioxide in arterial blood, PaO 2 /FiO 2 Ratio of partial pressure of oxygen in arterial blood to fraction of inspired oxygen, MAP Mean arterial pressure, HR Heart rate
  2. Data are expressed as median [IQR]
  3. Wilcoxon post hoc test analysis for couples: aStatistically significant difference from PEEP 5 incremental phase; bStatistically significant difference from PEEP 10 incremental phase; cStatistically significant difference from PEEP 15; dStatistically significant difference from PEEP 10 decremental phase