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Table 3 Primary and secondary outcomes according to initial oxygenation group

From: Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients: a cohort study

Outcome All subjects
n = 688
ED hypoxiaa
n = 38
ED normoxiab
n = 350
ED hyperoxiac
n = 300
Adjusted odds ratio or between-group difference (95% CI) P value
Primary outcome, n (%)
 Mortality 162 (23.5) 5 (13.2) 68 (19.4) 89 (29.7) 1.95 (1.34–2.85) <0.001
Secondary outcomes (days)
 Ventilator-free 16.5 (10.9) 20.3 (9.7) 17.9 (10.3) 14.2 (11.3) 3.7 (2.0–5.4) <0.001
 ICU-free 15.2 (10.3) 17.9 (9.1) 16.7 (9.8) 13.2 (10.7) 3.5 (1.9–5.1) <0.001
 Hospital-free 10.7 (9.2) 12.8 (9.3) 11.9 (9.0) 8.9 (9.1) 2.9 (1.5–4.3) <0.001
  1. The P value for the primary outcome measure was from the Wald test estimated using a logistic regression model accounting for age, gender, Acute Physiology and Chronic Health Evaluation II score, lactate, emergency department tidal volume, emergency department (ED) plateau pressure, intensive care unit partial pressure of arterial oxygen (PaO2), and oxygen exposure group. The P values for the secondary outcomes are from the independent sample t test, comparing the normoxic and hyperoxic groups
  2. aPaO2 < 60 mm Hg
  3. bPaO2 60–120 mm Hg
  4. cPaO2 > 120 mm Hg