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Table 2 Ventilator variables in the emergency department and day 1 in the intensive care unit

From: Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients: a cohort study

  All subjects
n = 688
ED hypoxiaa
n = 38
ED normoxiab
n = 350
ED hyperoxiac
n = 300
P value
Emergency department
 Tidal volume (mL/kg PBW) 7.5 (6.4–8.6) 6.6 (6.1–7.7) 7.5 (6.4–8.6) 7.6 (6.7–8.7) 0.001
 Respiratory rate 16 (14–20) 20 (16–25) 16 (14–20) 16 (14–20) <0.001
 FiO2 70 (47–100) 60 (40–80) 68 (40–100) 80 (50–100) 0.004
 PEEP 5 (5–7) 8 (5–10) 5 (5–7) 5 (5–5) <0.001
 pH 7.29 (7.21–7.38) 7.26 (7.16–7.33) 7.29 (7.21–7.38) 7.29 (7.21–7.39) 0.354
 PaO2 (mm Hg) 110 (82–179) 54 (51–55) 88 (76–101) 189 (146–249) <0.001
 PaO2/FiO2 192 (115–278) 106 (83–141) 129 (92–207) 270 (198–360) <0.001
 Plateau pressure (mmHg) 20 (17–25) 24 (20–28) 20 (17–25) 20 (17–25) 0.006
 Static compliance (mL/cm H20) 33 (26–45) 31 (24–36) 33 (25–45) 35 (26–46) 0.071
 Driving pressure (cm H2O) 14 (11–19) 15 (12–18) 14 (11–19) 14 (11–19) 0.117
Intensive care unit, day 1
 Tidal volume (mL/kg PBW) 8.0 (7.0–8.8) 7.5 (6.5–8.3) 8.0 (7.0–9.0) 7.7 (7.0–8.8) 0.220
 FiO2 46 (40–60) 46 (40–57) 46 (40–60) 46 (40–60) 0.616
 PEEP 5 (5–6) 6 (5–8) 5 (5–6) 5 (5–6) 0.002
 pH 7.35 (7.29–7.40) 7.38 (7.30–7.41) 7.35 (7.29–7.39) 7.35 (7.29–7.40) 0.377
 PaO2 (mm Hg) 97 (82–113) 96 (83–113) 94 (79–109) 100 (84–117) 0.002
 PaO2/FiO2 207 (163–258) 206 (169–244) 200 (156–257) 210 (170–260) 0.053
 Plateau pressure (mmHg) 21 (18–25) 22 (20–25) 21 (18–25) 21 (18–25) 0.266
 Static compliance (mL/cm H20) 35 (27–43) 33 (27–37) 34 (27–43) 35 (28–43) 0.181
 Driving pressure (cm H2O) 16 (13–19) 15 (13–18) 16 (13–19) 16 (13–19) 0.342
  1. Continuous variables are reported as median (interquartile range). P values are from one-way analysis of variance. Bonferroni correction: α/n of comparisons = 0.05/3 = 0.017. PBW predicted body weight, FiO 2 fraction of inspired oxygen, PEEP positive end-expiratory pressure, PaO 2 partial pressure of arterial oxygen
  2. aPartial pressure of arterial oxygen (PaO2) <60 mm Hg
  3. bPaO2 60–120 mm Hg
  4. cPaO2 > 120 mm Hg