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Table 2 Ventilator variables in the emergency department and day 1 in the intensive care unit

From: Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients: a cohort study

 

All subjects

n = 688

ED hypoxiaa

n = 38

ED normoxiab

n = 350

ED hyperoxiac

n = 300

P value

Emergency department

 Tidal volume (mL/kg PBW)

7.5 (6.4–8.6)

6.6 (6.1–7.7)

7.5 (6.4–8.6)

7.6 (6.7–8.7)

0.001

 Respiratory rate

16 (14–20)

20 (16–25)

16 (14–20)

16 (14–20)

<0.001

 FiO2

70 (47–100)

60 (40–80)

68 (40–100)

80 (50–100)

0.004

 PEEP

5 (5–7)

8 (5–10)

5 (5–7)

5 (5–5)

<0.001

 pH

7.29 (7.21–7.38)

7.26 (7.16–7.33)

7.29 (7.21–7.38)

7.29 (7.21–7.39)

0.354

 PaO2 (mm Hg)

110 (82–179)

54 (51–55)

88 (76–101)

189 (146–249)

<0.001

 PaO2/FiO2

192 (115–278)

106 (83–141)

129 (92–207)

270 (198–360)

<0.001

 Plateau pressure (mmHg)

20 (17–25)

24 (20–28)

20 (17–25)

20 (17–25)

0.006

 Static compliance (mL/cm H20)

33 (26–45)

31 (24–36)

33 (25–45)

35 (26–46)

0.071

 Driving pressure (cm H2O)

14 (11–19)

15 (12–18)

14 (11–19)

14 (11–19)

0.117

Intensive care unit, day 1

 Tidal volume (mL/kg PBW)

8.0 (7.0–8.8)

7.5 (6.5–8.3)

8.0 (7.0–9.0)

7.7 (7.0–8.8)

0.220

 FiO2

46 (40–60)

46 (40–57)

46 (40–60)

46 (40–60)

0.616

 PEEP

5 (5–6)

6 (5–8)

5 (5–6)

5 (5–6)

0.002

 pH

7.35 (7.29–7.40)

7.38 (7.30–7.41)

7.35 (7.29–7.39)

7.35 (7.29–7.40)

0.377

 PaO2 (mm Hg)

97 (82–113)

96 (83–113)

94 (79–109)

100 (84–117)

0.002

 PaO2/FiO2

207 (163–258)

206 (169–244)

200 (156–257)

210 (170–260)

0.053

 Plateau pressure (mmHg)

21 (18–25)

22 (20–25)

21 (18–25)

21 (18–25)

0.266

 Static compliance (mL/cm H20)

35 (27–43)

33 (27–37)

34 (27–43)

35 (28–43)

0.181

 Driving pressure (cm H2O)

16 (13–19)

15 (13–18)

16 (13–19)

16 (13–19)

0.342

  1. Continuous variables are reported as median (interquartile range). P values are from one-way analysis of variance. Bonferroni correction: α/n of comparisons = 0.05/3 = 0.017. PBW predicted body weight, FiO 2 fraction of inspired oxygen, PEEP positive end-expiratory pressure, PaO 2 partial pressure of arterial oxygen
  2. aPartial pressure of arterial oxygen (PaO2) <60 mm Hg
  3. bPaO2 60–120 mm Hg
  4. cPaO2 > 120 mm Hg