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Table 3 Bayesian NMA estimates of probability of superiority (P) and odds ratio (OR)

From: Antimicrobials for the treatment of drug-resistant Acinetobacter baumannii pneumonia in critically ill patients: a systemic review and Bayesian network meta-analysis

Treatment

All-cause mortality

Clinical cure

Microbiological eradication

P %

OR (95% CrI)

P %

OR (95% CrI)

P %

OR (95% CrI)

SUL

98.1*

0.27 (0.06–0.91)

80.4

1.45 (0.62–3.48)

98.9*

4.82 (1.22–25.83)

IH COL + IV COL

92.1

0.80 (0.58–1.10)

99.9*

1.67 (1.20–2.29)

90.4

1.28 (0.88–1.88)

FOS + IV COL

85.3

0.64 (0.28–1.45)

66.3

1.20 (0.52–2.72)

99.8*

15.2 (2.27–428.6)

HD SUL

74.5

0.56 (0.09–3.17)

70.1

1.54 (0.32–8.63)

38.3

0.79 (0.15–3.99)

HD TIG

65.1

0.81 (0.25–2.53)

91.8

2.48 (0.70–8.89)

36.4

0.77 (0.19–3.30)

RIF + IV COL

59.7

0.94 (0.56–1.54)

78.1

1.63 (0.48–5.54)

99.4*

1.88 (1.14–3.13)

IH COL

39.8

1.33 (0.12–13.87)

NA

NA

55.9

1.22 (0.09–19.93)

GLY + IV COL

35.3

1.13 (0.58–2.20)

14.9

0.55 (0.17–1.65)

21.6

0.62 (0.18–2.04)

TIG + IH COL

31.3

1.47 (0.26–8.32)

NA

NA

56.9

1.18 (0.18–7.40)

CAR + IV COL

21.1

1.58 (0.49–5.52)

14.2

0.50 (0.12–1.78)

78.1

1.57 (0.50–5.45)

CAR + IH COL

16.7

1.94 (0.48–8.19)

9.9

0.38 (0.08–1.64)

76.5

1.65 (0.42–7.06)

SUL + IH COL

14.2

2.32 (0.43–12.63)

NA

NA

90.4

3.37 (0.54–20.94)

SUL + IV COL

7.0

2.58 (0.71–9.88)

10.1

0.40 (0.09–1.60)

73.3

1.51 (0.42–5.75)

TIG

1.0*

1.75 (1.09–2.81)

38.7

0.89 (0.43–1.88)

1.7*

0.40 (0.16–0.94)

  1. Abbreviations: CAR carbapenem (imipenem or meropenem), COL colistin, CrI credible interval, FOS fosfomycin, GLY glycopeptide (vancomycin or teicoplanin), HD high-dose, IH inhaled, IV intravenous, NA not available, RIF rifampin, SUL sulbactam, TIG tigecycline
  2. *P > 97.5% and P < 2.5%, statistically significant superiority and inferiority, respectively