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Table 6 A two-stage approach to critical care

From: Time-sensitive therapeutics

• Rescue phase
 – Minimize demand and establish stability
 – Full support/gentle transitions
 – Take control (monotony may be needed)
• Adaptation phase
 – Intermittent stresses and rest periods
 – Ongoing targeted reductions of vital supports (acclimatize)
  – FiO2
  – Ventilating pressure
  – Vasopressors
  – Positioning
 – Encourage variability