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Table 4 Stepwise logistic regression models of dose dependency of categorical outcomes (KDIGO stages 1, 2, and 3)

From: Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients

 

KDIGO stage

 

1

2

3

Coefficients

Estimate

p

Estimate

p

Estimate

p

(Intercept)

–3.9249

< 0.0001

–4.6114

< 0.0001

–4.5883

< 0.0001

[D] PT

0.0036

0.0364

0.0058

0.0039

0.0136

0.0086

[D] V

–

–

–

–

–0.0585

0.1057

  1. All logistic models used stepwise variable selection based on minimization of Akaike Information Criterion and passed the Hosmer Lemeshow test for goodness of fit
  2. [D] PT average daily dose of piperacillin-tazobactam (mg/kg/day), [D] V average daily dose of vancomycin co-administered with PT (mg/kg/day), KDIGO Kidney Disease Improving Global Outcomes
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Critical Care

ISSN: 1364-8535