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Table 1 Blood pressure effect of angiotensin II from entire cohort

From: The effect of angiotensin II on blood pressure in patients with circulatory shock: a structured review of the literature

Author (year) Cases Total/+data Type of shock SBP ↑ (mmHg) MAP ↑ (mmHg) Dose range
Median
(IQR)
   Septic Other Cardiogenic    
Del Greco (1961) [25] 20/20 7 11 2 47.4   0.23–100 mcg/min
2.5 mcg/min
(13.5)
Nassif (1963) [34] 14/13 6 6 2 106.9   7–1500 mcg bolus
14 mcg/min
(32)
Wedeen (1963) [35] 15/7 1 3 11 81.1   1.5–36 mcg/min
10 mcg/min
(6.5)
Beanlands (1964) [36] 17/0 0 0 17 a   1–36 mcg/min
2 mcg/min
(2.25)
Udhoji (1964) [26] 12/6 4 5 3   34.3 b
Belle (1965) [37] 1/1 0 0 1 16.0   50–250 mg/day
-
-
Cohn (1965) [27] 6/6 6 0 0   29.7 b
Cohn (1965) [27] 22/22 0 22 0   22.1 0.3–60 mcg/min
14.1 mcg/min
-
Singh (1966) [28] 25/0 25 0 0 c   4–12 mcg/min
-
-
Wallace (1967) [29] 7/7 0 7 0   22.9 0.75- mcg/min
1.5 mcg/min
(0)
Sorensen (1986) [32] 8/0 0 8 0 d   b
Moore (1989) [33] 9/0 0 9 0 e   2.9 ng/kg/min
-
-
Geary (1990) [38] 1/1 0 0 1   30.0 6 mcg/min
-
-
Thacker (1990) 2/2 0 2 0   27.5 6–7 mcg/min
6.5 mcg/min
-
Thomas (1991) [40] 1/0 1 0 0   f 5–20 mcg/min
10 mcg/min
-
Jackson (1993) [20] 1/0 0 1 0 g   3–18 mcg/min
18 mcg/min
-
Trilli (1994) [21] 1/1 0 0 1 24.0   8.5–9 mcg/min
8.5 mcg/min
-
Ryding (1995) [41] 1/1 1 0 0   18.0 3.5–4.2 mcg/min
-
-
Newby (1995) [22] 1/1 0 1 0 30.0   0.8–2.2 mcg/min
22 ng/kg/min
-
Wray (1995) [24] 1/0 1 0 0   h 8–22 mcg/min
8 mcg/min
-
Tovar (1997) [23] 1/1 0 1 0 50.0   5–15 mcg/min
15 mcg/min
-
Eyraud (1998) [30] 14/14 0 14 0 74.0   2.5 mcg bolus
-
-
Chawla (2014) [10] 10/10 10 0 0   6.0 15–20 ng/kg/min
20 ng/kg/min
-
Khanna (2017) [11] 163/163 163 0 0   12.5 20–40 ng/kg/min
2.8 mg
(5.8)
Total 353/276 225 90 38 71.3i 14.8i  
  1. SBP systolic blood pressure, MAP mean arterial pressure, IQR interquartile range (in units similar to that study’s dose range)
  2. aFrom 52.8 mmHg to > 100 mmHg in 13 of 18 patients
  3. bData unavailable
  4. cFrom < 90 mmHg to > 90 mmHg
  5. dFrom BP of 76/48 mmHg to DBP of > 68 mmHg
  6. e20 mmHg increase from average SBP of 81.7 mmHg
  7. fFrom 52 mmHg to > 100 mmHg
  8. gFrom 50 mmHg to > 100 mmHg
  9. hFrom < 80 mmHg to > 80 mmHg
  10. iWeighted average