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Table 3 Independent predictive factors of 28-day and 90-day mortality in 779 patients admitted for acute decompensation of cirrhosis; multivariate analysis

From: Copeptin in acute decompensation of liver cirrhosis: relationship with acute-on-chronic liver failure and short-term survival

 

HR (95% CI)

p value

Mortality at 28 days

 Model 1: MELD score

  MELD score

1.10 (1.06–1.14)

< 0.001

  Copeptina

1.55 (1.20–2.01)

< 0.001

  WBCa

1.82 (1.23–2.95)

0.014

 Model 2: CLIF-C OF score

  CLIF-C OF score

1.43 (1.25–1.64)

< 0.001

  Copeptina

1.53 (1.19–1.97)

0.001

  WBCa

1.92 (1.18–3.13)

0.009

Mortality at 90 days

 Model 1: MELD score

  MELD score

1.11 (1.07–1.15)

< 0.001

  Copeptina

1.15 (0.97–1.37)

0.113

  Age

1.03 (1.01–1.05)

0.006

  WBCa

1.77 (1.26–2.47)

< 0.001

  Sodium

0.96 (0.93–0.99)

0.041

 Model 2: CLIF-C OF score

  CLIF-C OF score

1.39 (1.23–1.56)

< 0.001

  Copeptina

1.22 (1.02–1.45)

0.032

  Age

1.02 (1.00–1.04)

0.032

  WBCa

1.87 (1.32–2.65)

< 0.001

  Sodium

0.95 (0.92–0.98)

0.002

  1. aVariable was log-transformed prior to statistical analysis
  2. CI confidence interval, CLIF-C OF chronic liver failure-consortium organ failure, HR hazard ratio, MELD Model for End-stage Liver Disease, WBC white blood cell count