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Table 1 Baseline characteristics for survival to hospital discharge and good neurological recovery

From: Initial blood pH during cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients: a multicenter observational registry-based study

 

Survival to hospital discharge

Good neurological recovery

Yes (n = 311)

No (n = 1918)

p Value

Yes (n = 98)

No (n = 2131)

p Value

Sex

  

0.015

  

0.01

 Male, n (%)

219 (15.3)

1214 (84.7)

 

75 (5.2)

1358 (94.8)

 

 Female, n (%)

92 (11.6)

704 (88.4)

 

23 (2.9)

773 (97.1)

Age, years, mean (IQR)

59 (49–73)

66 (51–76)

0.001

55 (46–65)

66 (51–76)

< 0.001

Prehospital CPR duration, minutes, mean (IQR)

20 (14–25)

23 (13–30)

< 0.001

16 (9–24)

23 (12–30)

< 0.001

ACLS duration, minutes, mean (IQR)

12 (6–20)

21 (13–30)

< 0.001

10 (4–21)

20 (12–30)

< 0.001

Witnessed arrest, n (%)

214 (68.8)

1054 (55)

< 0.001

82 (83.7)

1186 (55.7)

< 0.001

Cardiac origin, n (%)

123 (39.5)

719 (38.9)

0.486

58 (59.2)

784 (36.8)

< 0.001

Bystander CPR, n (%)

129 (41.5)

747 (38.9)

0.396

49 (50)

827 (38.8)

0.027

Shockable rhythm (ED), n (%)

68 (21.9)

149 (7.8)

< 0.001

51 (52)

166 (7.8)

< 0.001

TTM, n (%)

160 (51.4)

208 (10.8)

< 0.001

57 (58.2)

311 (14.6)

< 0.001

Emergent CAG, n (%)

46 (14.8)

55 (2.9)

< 0.001

29 (29.6)

72 (3.4)

< 0.001

Emergent PCI, n (%)

29 (9.3)

32 (1.7)

< 0.001

20 (20.4)

41 (1.9)

<0.001

pH, mean (IQR)

7.00 (6.93–7.31)

6.96 (6.83–7.20)

< 0.001

7.11 (7.00–7.26)

6.96 (6.84–7.09)

< 0.001

pCO2 (mmHg), mean (IQR)

70 (47–88)

72 (54–93)

0.01

60 (39–74)

72 (54–93)

< 0.001

pO2 (mmHg), mean (IQR)

48 (17–87)

30 (15–59)

< 0.001

53 (21–84)

30 (15–61)

< 0.001

HCO3 − (mEq/L), mean (IQR)

19 (15–22)

17 (13–21)

< 0.001

17 (14–22)

17 (13–21)

0.308

Lactate (mmol/L), mean (IQR)

9.5 (6.9–11.7)

10.1 (7.1–13.6)

0.006

8.7 (6.8–10.8)

10.1 (7.1–13.4)

0.011

Sodium (mmol/L), mean (IQR)

140 (136–142)

140 (136–143)

0.685

140 (136–142)

140 (136–143)

0.974

Potassium (mmol/L), mean (IQR)

4.9 (4.0–6.0)

6.9 (4.7–7.4)

< 0.001

4.3 (3.7–5.3)

5.8 (4.6–7.2)

< 0.001

Chloride (mmol/L), mean (IQR)

105 (100–108)

104 (99–108)

< 0.071

106 (101–109)

104 (99–108)

0.016

Total CO2 (mmol/L), mean (IQR)

18 (14–22)

16 (11–20)

< 0.001

17 (14–20)

16 (11–20)

0.014

Glucose (mg/dL), mean (IQR)

223 (152–304)

215 (122–309)

0.044

197 (152–268)

217 (126–310)

0.707

  1. Abbreviations: CPR Cardiopulmonary resuscitation, ACLS Advanced cardiovascular life support, ED Emergency department, TTM Targeted temperature management, CAG Coronary angiography, PCI Percutaneous coronary intervention, HCO 3 − Bicarbonate, pCO 2 Partial pressure of carbon dioxide, pO 2 Partial pressure of oxygen
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