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Table 3 Catheter outcomes: colonization and CRBSI

From: Comparison of the efficacy of three topical antiseptic solutions for the prevention of catheter colonization: a multicenter randomized controlled study

(a) No. of catheters and incidence per 1000 catheter-days
  All
N = 796
0.5% CHG
N = 261
1.0% CHG
N = 278
10% PVI
N = 257
P value
Colonization
 Number of catheters (%) 24 (3.0%) 5 (1.9%) 6 (2.2%) 13 (5.1%) 0.07
 Incidence per 1000 catheter-days, n (95% CI) 5.8 (3.5–8.2) 3.7 (0.5–6.9) 3.9 (0.8–7.0) 10.5 (4.8–16.3) 0.03
CRBSI
 Number of catheters (%) 13 (1.6%) 4 (1.5%) 3 (1.1%) 6 (2.3%) 0.51
 Incidence, per 1000 catheter-days, n (95% CI) 3.2 (1.4–4.9) 3.0 (0.1–5.8) 2.0 (0–4.2) 4.9 (1.0–8.8) 0.41
(b) Hazard ratio for each combination of antiseptic solution  
  Colonization CRBSI
HR (95% CI) P value HR (95% CI) P value
0.5% CHG vs. 10% PVI 0.33 (0.12–0.95) 0.04 0.63 (0.18–2.22) 0.47
1.0% CHG vs. 10% PVI 0.35 (0.13–0.93) 0.04 0.41 (0.10–1.63) 0.20
0.5% CHG vs. 1.0% CHG 0.95 (0.29–3.13) 0.94 1.54 (0.35–6.90) 0.57
  1. CHG chlorhexidine gluconate, PVI povidone-iodine, HR hazard ratio, CI confidence interval, CRBSI catheter-related bloodstream infection