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Table 3 Catheter outcomes: colonization and CRBSI

From: Comparison of the efficacy of three topical antiseptic solutions for the prevention of catheter colonization: a multicenter randomized controlled study

(a) No. of catheters and incidence per 1000 catheter-days

 

All

N = 796

0.5% CHG

N = 261

1.0% CHG

N = 278

10% PVI

N = 257

P value

Colonization

 Number of catheters (%)

24 (3.0%)

5 (1.9%)

6 (2.2%)

13 (5.1%)

0.07

 Incidence per 1000 catheter-days, n (95% CI)

5.8 (3.5–8.2)

3.7 (0.5–6.9)

3.9 (0.8–7.0)

10.5 (4.8–16.3)

0.03

CRBSI

 Number of catheters (%)

13 (1.6%)

4 (1.5%)

3 (1.1%)

6 (2.3%)

0.51

 Incidence, per 1000 catheter-days, n (95% CI)

3.2 (1.4–4.9)

3.0 (0.1–5.8)

2.0 (0–4.2)

4.9 (1.0–8.8)

0.41

(b) Hazard ratio for each combination of antiseptic solution

 
 

Colonization

CRBSI

HR (95% CI)

P value

HR (95% CI)

P value

0.5% CHG vs. 10% PVI

0.33 (0.12–0.95)

0.04

0.63 (0.18–2.22)

0.47

1.0% CHG vs. 10% PVI

0.35 (0.13–0.93)

0.04

0.41 (0.10–1.63)

0.20

0.5% CHG vs. 1.0% CHG

0.95 (0.29–3.13)

0.94

1.54 (0.35–6.90)

0.57

  1. CHG chlorhexidine gluconate, PVI povidone-iodine, HR hazard ratio, CI confidence interval, CRBSI catheter-related bloodstream infection