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Table 1 Characteristics of study participants

From: Comparison of the efficacy of three topical antiseptic solutions for the prevention of catheter colonization: a multicenter randomized controlled study

Characteristic

All

N = 796

0.5% CHG

N = 261

1.0% CHG

N = 278

10% PVI

N = 257

Age, mean (SD), years

66.2 (16.3)

65.7 (16.3)

65.9 (16.3)

67.1 (16.4)

Gender, male (n, %)

504 (63.3%)

162 (62.1%)

187 (67.3%)

155 (60.3%)

APACHE 2, mean (SD)

21.0 (8.5)

21.0 (8.6)

21.5 (8.6)

20.5 (8.4)

SAPS 2, mean (SD)

49.4 (18.6)

48.5 (19.2)

50.9 (18.2)

48.8 (18.4)

SOFA, mean (SD)

7.2 (4.0)

7.1 (3.9)

7.5 (4.3)

7.0 (3.9)

Comorbidities (n, %)

 Immunodeficiency

39 (4.9%)

10 (3.8%)

17 (6.1%)

12 (4.7%)

 Steroid administration

90 (11.3%)

32 (12.3%)

35 (12.6%)

23 (9.0%)

 Trauma

64 (8.0%)

27 (10.3%)

16 (5.8%)

21 (8.2%)

 Cancer

84 (10.6%)

29 (11.1%)

31 (11.2%)

24 (9.3%)

 Diabetes

153 (19.2%)

57 (21.8%)

51 (18.4%)

45 (17.5%)

 HIV

1 (0.1%)

0 (0%)

1 (0.4%)

0 (0%)

 Cirrhosis

40 (5.0%)

13 (5.0%)

14 (5.0%)

13 (5.1%)

 Acute kidney injury

245 (30.8%)

85 (32.6%)

81 (29.1%)

79 (30.7%)

 Chronic kidney disease

137 (17.2%)

51 (19.5%)

47 (16.9%)

39 (15.2%)

Admission category (n, %)

 Medical

645 (81.0%)

203 (77.8%)

231 (83.1%)

211 (82.1%)

 Scheduled surgery

23 (2.9%)

9 (3.5%)

5 (1.8%)

9 (3.5%)

 Emergency surgery

128 (16.1%)

49 (18.8%)

42 (15.1%)

37 (14.4%)

Infections before catheter insertion (n, %)

448 (56.3%)

150 (57.5%)

162 (58.3%)

136 (52.9%)

Origin of infection (n, %)

 Central nervous system

4 (0.5%)

1 (0.4%)

2 (0.7%)

1 (0.4%)

 Pulmonary

195 (24.5%)

69 (26.5%)

63 (22.7%)

63 (24.5%)

 Cardiovascular

5 (0.6%)

2 (0.8%)

2 (0.7%)

1 (0.4%)

 Abdominal

92 (11.6%)

23 (8.9%)

44 (15.8%)

25 (9.7%)

 Urinary tract

44 (5.5%)

19 (7.3%)

10 (3.6%)

15 (5.8%)

 Skin

14 (1.8%)

7 (2.7%)

3 (1.1%)

4 (1.6%)

 Catheter

8 (1.0%)

2 (0.8%)

5 (1.8%)

1 (0.4%)

 Others

82 (10.3%)

25 (9.6%)

31 (11.2%)

26 (10.1%)

 None

351 (44.2%)

112 (43.1%)

118 (42.5%)

121 (47.1%)

Antibiotics before catheter insertion (n, %)

445 (55.9%)

153 (58.6%)

155 (55.8%)

137 (53.3%)

  1. CHG chlorhexidine gluconate, PVI povidone-iodine, SD standard deviation, APACHE acute physiology and chronic health evaluation, SAPS simplified acute physiology score, SOFA sequential organ failure assessment, HIV human immunodeficiency virus