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Table 2 Clinical parameters related to mechanical ventilation and extracorporeal membrane oxygenation support

From: Extracorporeal membrane oxygenation for life-threatening asthma refractory to mechanical ventilation: analysis of the Extracorporeal Life Support Organization registry

Variables

Total

N = 272

Survivor

N = 227

Non-survivor

N = 45

p

ECMO modea

 VV

131 (50.4)

110 (50.7)

21 (48.8)

0.824

 VVDL

113 (43.5)

94 (43.3)

19 (44.2)

0.916

 VV to VA

3 (1.2)

1 (0.5)

2 (4.7)

0.019

 VA

5 (1.9)

5 (2.3)

0

0.315

 VVDL + V

6 (2.3)

5 (2.3)

1 (2.3)

0.993

 Other

2 (0.8)

2 (9.2)

0

0.527

 Hours on ECMO

176.4 ± 192.7

161.6 ± 172.1

257.2 ± 268.4

0.035

Post-ECMO ventilator settingb

 Rate, breaths/min

11.3 ± 4.3

11.1 ± 4.2

12.7 ± 5.0

0.043

 FiO2, %

48.8 ± 19.0

47.4 ± 17.8

57.4 ± 23.6

0.025

 PIP, cmH2O

25.0 ± 7.8

24.3 ± 4.5

29.7 ± 8.3

< 0.001

 PEEP, cmH2O

8.1 ± 4.5

7.9 ± 4.5

9.0 ± 4.0

0.195

 MAP, cmH2O

14.2 ± 10.0

14.2 ± 10.4

14.6 ± 6.2

0.866

 Driving pressure, cmH2O

16.8 ± 7.8

16.2 ± 7.8

21.1 ± 6.6

0.002

  1. Values are shown as number (%) or mean ± SD
  2. ECMO extracorporeal membrane oxygenation, FiO 2 fraction of inspired oxygen saturation, HCO 3 - arterial bicarbonate level, MAP mean airway pressure, PEEP positive end-expiratory pressure, PIP peak inspiratory pressure, PO 2 partial pressure of arterial oxygen, SaO 2 arterial oxygen saturation, VV venovenous, VVDL venovenous double lumen, VA venoarterial, VVDL + V double lumen venovenous ECMO with a cephalic draining cannula
  3. aAvailable in 260 patients
  4. bThe best values in the last 24 h were collected