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Table 2 Cardiovascular and respiratory parameters at inclusion

From: Change in cardiac output during Trendelenburg maneuver is a reliable predictor of fluid responsiveness in patients with acute respiratory distress syndrome in the prone position under protective ventilation

Parameters

Overall population (n = 33)

Fluid non-responders (n = 18)

Fluid responders (n = 15)

p

Norepinephrine administration

28 (85%)

17 (94%)

11 (73%)

0.15

Norepinephrine dose (μg.kg-1.min-1)

0.98 (0.41–1.50)

0.68 (0.35–1.04)

1.32 (0.71–1.97)

0.12

Dobutamine administration

7 (21%)

4 (22%)

3 (20%)

1

Dobutamine dose (μg.kg-1.min-1)

10.0 (7.5–14.8)

11.4 (8.8–13.8)

10.0 (5.2–14.9)

0.86

Heart rate (min-1)

100 (93–115)

102 (92–117)

100 (93–112)

0.69

MAP (mm Hg)

69 (64–72)

67 (62–71)

70 (68–72)

0.14

PPV (%)a

7 (5–10)

7 (5–8)

7 (5–11)

0.92

CVP (mm Hg)

7 (5–11)

7 (5–10)

7 (4–11)

0.93

CITPTD (L.min-1.m-2)

2.75 (2.06–3.50)

2.94 (2.26–3.50)

2.70 (2.04–3.04)

0.48

GEDVI (ml.m-2)

701 (587–854)

697 (586–866)

701 (614–773)

0.89

ELWI (ml.kg-1 PBW)

14.6 (11.8–20.4)

15.8 (12.6–20.9)

13.7 (10.1–18.3)

0.23

Global ejection fraction (%)

16 (13–18)

16 (14–20)

16 (13–17)

0.66

Respiratory rate (min-1)

30 (28–35)

30 (28–35)

30 (28–35)

0.84

Heart rate/respiratory rate ≤3.6

20 (61%)

10 (56%)

10 (67%)

0.72

Tidal volume (ml.kg-1 PBW)

6.0 (5.9–6.1)

6.0 (6.0–6.1)

6.0 (5.9–6.0)

0.31

PEEP (cm H2O)

8 (5–10)

8 (6–10)

8 (6–10)

0.67

PEEPt,rs (cm H2O)

9 (8–11)

9 (8–11)

10 (8–12)

0.83

Pplat,rs (cm H2O)

22 (20–27)

22 (20–28)

22 (18–26)

0.54

Driving pressure (cm H2O)

12 (10–15)

13 (10–18)

11 (9–14)

0.23

Cst,rs (mL.cm H2O-1)

30 (23–39)

28 (21–38)

31 (25–43)

0.26

pH

7.33 (7.27–7.38)

7.31 (7.27–7.36)

7.38 (7.28–7.42)

0.20

PaO2/FiO2 (Torr)

158 (120–208)

155 (120–167)

207 (109–241)

0.17

PaCO2 (Torr)

41 (38–51)

46 (41–52)

38 (36–44)

0.06

Arterial lactate (mmol.L-1)

2.5 (1.9–6.4)

2.5 (1.9–6.3)

2.5 (1.8–5.8)

0.94

  1. Data are median (1st quartile to 3rd quartile) or count (percentage)
  2. CI TPTD cardiac index assessed by transpulmonary thermodilution, Cst,rs static compliance of the respiratory system, CVP central venous pressure, ELWI extravascular lung water index, FiO 2 inspired oxygen fraction, GEDVI global end-diastolic volume index, MAP mean arterial pressure, PaO 2 partial pressure of arterial oxygen, PaCO 2 partial pressure of arterial carbon dioxide, PBW predicted body weight, PEEP positive end-expiratory pressure, PEEPt,rs total PEEP of the respiratory system, Pplat,rs plateau pressure of the respiratory system
  3. aFor patients without cardiac arrhythmia