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Table 1 Collation of recent studies with blood urea level criteria in exclusion or intervention

From: An isolated elevation in blood urea level is not ‘uraemia’ and not an indication for renal replacement therapy in the ICU

Study

Year

Urea exclusion criteria

Late RRT urea intervention threshold

Zarbock et al. [5]

2016

None

Serum urea > 100 mg/dL (35.7 mmol/L)

Gaudry et al. [3]

2016

Urea blood > 112 mg/dL (40 mmol/L)

Urea blood > 112 mg/dL (40 mmol/L)

Combes et al. [2]

2015

None

Serum urea > 36 mmol/L

Jamale et al. [4]

2013

Life-threatening uremic complications (alteration of higher mental function attributable to uraemia, and pericarditis)

Uremic nausea

Bagshaw et al. [14]

2009

None

Serum urea > 24.2 mmol/L

Bouman et al. [1]

2002

None

Serum urea > 40 mmol/L

Pursnani et al. [15]

1997

Urea blood > 120 mg/dL (42.8 mmol/L)

Serum urea > 40 mmol/L