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Table 2 Effect of variables, including age and sex, in a logistic regression model and an interaction model

From: The impact of sex and age on neurological outcomes in out-of-hospital cardiac arrest patients with targeted temperature management

 

Univariate analysis

Multivariate analysisa

Interaction analysisb

OR

95% CI

p Value

OR

95% CI

p Value

OR

95% CI

p Value

Good neurological outcome

 Male sex

1.74

1.24–2.44

0.001

1.44

0.93–2.23

0.099

3.74

0.85–16.35

0.080

 Age, per year

0.96

0.95–0.97

< 0.001

0.94

0.93–0.96

< 0.001

0.95

0.93–0.98

< 0.001

 Witnessed

2.76

1.93–3.94

< 0.001

1.75

1.11–2.77

0.016

1.74

1.10–2.75

0.017

 Bystander CPR

1.85

1.37–2.52

< 0.001

0.81

0.53–1.24

0.333

0.81

0.53–1.23

0.316

 Shockable rhythm

7.40

5.36–10.22

< 0.001

4.47

2.94–6.79

< 0.001

4.48

2.95–6.82

< 0.001

 Cardiac cause

7.78

5.11–11.85

< 0.001

6.00

3.53–10.20

< 0.001

5.95

3.50–10.12

< 0.001

 Anoxic time, per minute

0.96

0.95–0.97

< 0.001

0.94

0.93–0.96

< 0.001

0.94

0.93–0.96

< 0.001

 Early coronary angiography

2.77

1.87–4.09

< 0.001

1.34

0.81–2.23

0.260

1.31

0.78–2.18

0.303

 Age × sex

      

0.98

0.96–1.01

0.183

Survival to discharge

 Male

1.74

1.31–2.31

0.001

1.71

1.24–2.35

0.001

2.16

0.69–6.76

0.187

 Age, per year

0.98

0.97–0.99

< 0.001

0.97

0.96–0.98

< 0.001

0.98

0.96–0.99

0.001

 Witnessed

2.23

1.69–2.95

< 0.001

1.86

1.34–2.57

< 0.001

1.86

1.34–2.57

< 0.001

 Bystander CPR

1.21

0.91–1.62

0.190

0.68

0.48–0.95

0.026

0.68

0.48–0.95

0.025

 Shockable rhythm

3.58

2.57–4.99

< 0.001

2.19

1.48–3.26

< 0.001

2.19

1.47–3.25

< 0.001

 Cardiac cause

2.86

2.18–3.76

< 0.001

2.06

1.48–2.87

< 0.001

2.05

1.47–2.86

< 0.001

 Anoxic time, per minute

0.98

0.97–0.99

< 0.001

0.98

0.97–0.98

< 0.001

0.98

0.97–0.98

< 0.001

 Early coronary angiography

2.00

1.31–3.05

0.001

1.10

0.68–1.80

0.695

1.10

0.67–1.80

0.707

 Age × sex

      

1.00

0.98–1.02

0.673

  1. CPR Cardiopulmonary resuscitation
  2. aAdjusted for sex, age, bystander-witnessed status, bystander cardiopulmonary resuscitation performance, first recorded rhythm during cardiac arrest, presumed arrest cause, anoxic time, and early coronary angiography
  3. bAdjusted for covariates in the multivariate analysis and interaction term (age × sex)