Table 1 Study population characteristics throughout the intervention
Variable | Baseline (n = 384) | Second quarter (n = 288) | Third quarter (n = 422) | Fourth quarter (n = 531) | Fifth quarter (n = 563) | Sixth quarter (n = 492) | Seventh quarter (n = 398) | Eighth quarter (n = 357) | p Valuea |
|---|---|---|---|---|---|---|---|---|---|
Age, years | 61.0 (46.0–75.2) | 62.5 (47.0–75.0) | 63.0 (49.2–75.0) | 61.0 (48.0–74.0) | 60.0 (46.0–74.0) | 60.0 (44.0–74.0) | 61.0 (46.2–74.0) | 62.0 (50.0–74.5) | 0.133 |
Male sex | 223 (58.1) | 157 (54.5) | 240 (56.9) | 293 (55.2) | 326 (57.9) | 270 (54.9) | 227 (57.0) | 197 (55.2) | 0.802 |
Comorbidities | |||||||||
Diabetes | 98 (25.5) | 71 (24.7) | 108 (25.6) | 141 (26.6) | 148 (26.3) | 111 (22.6) | 90 (22.6) | 75 (21.0) | 0.216 |
Immunosuppression | 66 (17.2) | 38 (13.2) | 81 (19.2) | 96 (18.1) | 95 (16.9) | 89 (18.1) | 88 (22.1) | 85 (23.8) | 0.380 |
COPD | 41 (10.7) | 28 (9.7) | 41 (9.7) | 35 (6.6) | 44 (7.8) | 24 (4.9) | 20 (5.0) | 23 (6.4) | 0.133 |
CRF | 43 (11.2) | 37 (12.8) | 55 (13.0) | 81 (15.3) | 64 (11.4) | 43 (8.7) | 42 (10.6) | 42 (11.8) | <0.0001 |
Cancer | 45 (11.7) | 28 (9.7) | 51 (12.1) | 58 (10.9) | 54 (9.6) | 52 (10.6) | 66 (16.8) | 60 (16.8) | 0.330 |
Arterial hypertension | 183 (47.7) | 134 (46.5) | 186 (44.1) | 234 (44.1) | 243 (43.2) | 185 (37.6) | 143 (35.9) | 142 (39.8) | 0.004 |
Type of patient | 0.343 | ||||||||
Medical | 281 (73.2) | 191 (66.3) | 325 (77.0) | 418 (78.7) | 411 (73.0) | 358 (72.8) | 295 (74.1) | 288 (80.7) | |
Surgical | 103 (26.8) | 97 (33.7) | 97 (23.0) | 113 (21.3) | 152 (27.0) | 134 (27.2) | 103 (25.9) | 69 (19.3) | |
Source of infection | |||||||||
Pneumonia | 248 (64.6) | 157 (54.5) | 260 (61.6) | 302 (56.9) | 328 (58.3) | 250 (50.8) | 185 (46.5) | 197 (55.2) | 0.493 |
Urinary tract | 61 (15.9) | 55 (19.1) | 60 (14.2) | 95 (17.9) | 89 (15.8) | 90 (18.3) | 69 (17.3) | 53 (14.8) | <0.0001 |
Abdominal | 67 (17.4) | 51 (17.7) | 61 (14.5) | 63 (11.9) | 79 (14.0) | 90 (18.3) | 78 (19.6) | 45 (12.6) | 0.893 |
Type of infection | 0.078 | ||||||||
Community | 238 (62.0) | 168 (58.3) | 230 (54.5) | 280 (52.7) | 339 (60.2) | 284 (57.7) | 226 (56.8) | 233 (65.3) | |
Nosocomial | 146 (38.0) | 120 (41.7) | 192 (45.5) | 251 (47.3) | 224 (39.8) | 208 (42.3) | 172 (43.2) | 124 (34.7) | |
Location at presentation | <0.0001 | ||||||||
Emergency department | 184 (47.9) | 114 (39.6) | 179 (42.4) | 224 (42.2) | 247 (43.9) | 232 (47.2) | 201 (50.5) | 248 (69.5) | |
Ward | 145 (37.8) | 129 (44.8) | 184 (43.6) | 221 (41.6) | 219 (38.9) | 174 (35.4) | 141 (35.4) | 65 (18.2) | |
ICU | 55 (14.3) | 45 (15.6) | 59 (14.0) | 86 (16.2) | 97 (17.2) | 86 (17.5) | 56 (14.1) | 44 (12.3) | |