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Fig. 5 | Critical Care

Fig. 5

From: 6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice

Fig. 5

Hydroxyethyl starch (HES) 130/0.4 effects on the vascular permeability during pulmonary inflammation. Wild-type mice were exposed to nebulized saline or lipopolysaccharide (LPS) (n = 8). Sixty minutes after the procedure, mice received 20 ml/kg Isolyte® (Iso) or HES 130/0.4 (HES) as an infusion over 1 h. At 4, 8, and 24 h after the operation, vascular permeability in the (a) lung, (b) liver, (c) kidney, and (d) brain was measured by photometry using the extravasation of Evans blue technique. Data are presented as mean ± SEM, * p < 0.05

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