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Fig. 2 | Critical Care

Fig. 2

From: 6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice

Fig. 2

Hydroxyethyl starch (HES) 130/0.4 effects on syndecan-1, heparanase, and hyaluronic acid plasma levels during pulmonary inflammation. Wild-type mice were exposed to nebulized saline or lipopolysaccharide (LPS) (n = 8). Sixty minutes after the procedure, mice received 20 ml/kg Isolyte® (Iso) or HES 130/0.4 (HES) as an infusion over 1 h. The plasma levels of (a) syndecan-1, (b) heparanase, and (c) hyaluronic acid were analyzed 4, 8, and 24 h after the procedure. Data are presented as mean ± SEM, * p < 0.05

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Critical Care

ISSN: 1364-8535