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Fig. 2 | Critical Care

Fig. 2

From: Aerosol delivery during invasive mechanical ventilation: a systematic review

Fig. 2

Anteroposterior acquisition using planar scintigraphy for radiolabeled aerosol deposition assessment in an intubated patient after open-heart surgery (from Thomas et al. [37], with permission) (a), a tracheotomised critically ill patient (from O’Riordan et al. [35], with permission) (b) and three intubated neurosurgical patients ventilated in volume control mode (from Dugernier et al. [18] with permission) (c). Even if lung outlines suggested that inhaled drugs reached the lung periphery, these images illustrate that the majority of drugs impacted proximally in the artificial airways and particularly in the trachea and large bronchi. High deposition in the endotracheal tube, the trachea and the main bronchi has been masked to improve lung definition (a)

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