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Table 1 Patient characteristics

From: Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis

Characteristics Data
Age, years 64 [52–74]
Male sex, n (%) 156 (61)
APACHE II scorea 16 [10–23]
SOFA scoreb 5 [3–8]
ICU mortality, n (%) 53 (20.6)
In-hospital mortality, n (%) 70 (27.2)
Time in ICU before SDF imaging, days 4.0 [0.8–9.0]
<24 h in ICU before SDF imaging, n (%) 79 (30.7)
Reason for ICU admission, n (%)
 Surgery 91 (35.4)
 Sepsis 45 (17.5)
 Cardiac disease 18 (7.0)
 Neurological disorders 27 (10.5)
 Trauma 30 (11.7)
 Respiratory insufficiency 21 (8.2)
 Other 25 (9.7)
 Arterial lactate, mmol/L 1.04 [0.80–1.40]
 Hemoglobin, mmol/L 6.2 [5.4–7.0]
Vasopressor drugs
 Patients treated, n (%) 89 (34.6)
 Cumulative vasopressor indexc 3 [2–4]
Mechanical ventilation, n (%) 161 (63)
Abnormal microcirculationd, n (%) 36 (14)
MFI small vessels, AU 2.9 [2.7–3.0]
MFI large vessels, AU 3.0 [2.9–3.0]
TVD, mm/mm2 (small vessels) 18.9 [15.7–21.2]
PVD, mm/mm2 (small vessels) 18.1 [15.0–20.6]
PPV, % (small vessels) 98 [95–99]
De Backer score (small vessels) 11.3 ± 2.5
De Backer score (perfused small vessels) 10.9 ± 2.4
Heterogeneity index (small vessels) 0.07 [0.00–0.25]
  1. Abbreviations: APACHE II Acute Physiology and Chronic Health Evaluation II, ICU Intensive care unit, MFI Microvascular flow index, PPV Percentage of perfused vessels, PVD Perfused vessel density, SDF Sidestream dark-field imaging, SOFA Sequential Organ Failure Assessment, TVD Total vessel density
  2. Values are mean ± SD or median [IQR] unless specified otherwise. Cutoff value for small vessels < 20 μm
  3. aAPACHE II scores range from 0 to 71, with higher values indicating more severe disease
  4. bSOFA scores range from 0 to 4 for each organ system, with higher scores indicating more severe organ dysfunction
  5. cTrzeciak et al. [30]
  6. dAbnormal microcirculation defined as small vessel MFI < 2.6