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Table 1 Patient characteristics

From: Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis

Characteristics

Data

Age, years

64 [52–74]

Male sex, n (%)

156 (61)

APACHE II scorea

16 [10–23]

SOFA scoreb

5 [3–8]

ICU mortality, n (%)

53 (20.6)

In-hospital mortality, n (%)

70 (27.2)

Time in ICU before SDF imaging, days

4.0 [0.8–9.0]

<24 h in ICU before SDF imaging, n (%)

79 (30.7)

Reason for ICU admission, n (%)

 Surgery

91 (35.4)

 Sepsis

45 (17.5)

 Cardiac disease

18 (7.0)

 Neurological disorders

27 (10.5)

 Trauma

30 (11.7)

 Respiratory insufficiency

21 (8.2)

 Other

25 (9.7)

 Arterial lactate, mmol/L

1.04 [0.80–1.40]

 Hemoglobin, mmol/L

6.2 [5.4–7.0]

Vasopressor drugs

 Patients treated, n (%)

89 (34.6)

 Cumulative vasopressor indexc

3 [2–4]

Mechanical ventilation, n (%)

161 (63)

Abnormal microcirculationd, n (%)

36 (14)

MFI small vessels, AU

2.9 [2.7–3.0]

MFI large vessels, AU

3.0 [2.9–3.0]

TVD, mm/mm2 (small vessels)

18.9 [15.7–21.2]

PVD, mm/mm2 (small vessels)

18.1 [15.0–20.6]

PPV, % (small vessels)

98 [95–99]

De Backer score (small vessels)

11.3 ± 2.5

De Backer score (perfused small vessels)

10.9 ± 2.4

Heterogeneity index (small vessels)

0.07 [0.00–0.25]

  1. Abbreviations: APACHE II Acute Physiology and Chronic Health Evaluation II, ICU Intensive care unit, MFI Microvascular flow index, PPV Percentage of perfused vessels, PVD Perfused vessel density, SDF Sidestream dark-field imaging, SOFA Sequential Organ Failure Assessment, TVD Total vessel density
  2. Values are mean ± SD or median [IQR] unless specified otherwise. Cutoff value for small vessels < 20 μm
  3. aAPACHE II scores range from 0 to 71, with higher values indicating more severe disease
  4. bSOFA scores range from 0 to 4 for each organ system, with higher scores indicating more severe organ dysfunction
  5. cTrzeciak et al. [30]
  6. dAbnormal microcirculation defined as small vessel MFI < 2.6