All patients (n = 130) | MAKE (n = 41) | No MAKE (n = 89) | p Value | |
---|---|---|---|---|
Age, years | 48.5 (34–61.8) | 53 (47–67) | 44 (29–58) | 0.02 |
Sex, n (%) | ||||
Male | 80 (61.5) | 24 (58.5) | 56 (62.9) | 0.7 |
Female | 50 (38.5) | 17 (41.5) | 33 (37.1) | |
BMI, kg/m2 | 25.1 (22.7–28.5) | 26.2 (22.8–30.6) | 24.9 (22.7–27.5) | 0.06 |
Co-morbidities, n (%) | ||||
Hypertension | 27 (20.8) | 13 (31.7) | 14 (15.7) | 0.06 |
Diabetes mellitus | 16 (12.3) | 8 (19.5) | 8 (9) | 0.15 |
Chronic kidney disease | 2 (1.5) | 1 (2.4) | 1 (1.1) | 0.53 |
Vascular disease | 8 (6.2) | 3 (7.3) | 5 (5.6) | 0.71 |
Obesity | 21 (16.1) | 12 (29.3) | 9 (10.1) | 0.01 |
Smoking | 14 (10.8) | 2 (4.9) | 12 (13.5) | 0.22 |
Alcohol consumption | 15 (11.5) | 5 (12.2) | 10 (11.2) | 1 |
Psychiatric | 17 (13.1) | 6 (14.6) | 11 (12.4) | 0.78 |
Burn type, n (%) | ||||
Thermal | 123 (94.6) | 41 (100) | 82 (92.1) | 0.1 |
Electrical | 7 (5.4) | 0 (0) | 7 (7.9) | |
Body surface area burned (%) | ||||
Total | 28.5 (15–50.8) | 50 (22.5–70) | 20 (12–40) | <0.0001 |
Full thickness | 15 (4–32.2) | 25 (15–56) | 8 (1.8–25) | <0.0001 |
ICU length of stay, days | 27.5 (10–42.5) | 18 (3–38) | 29 (13.2–45) | 0.42 |
Death in ICU, n (%) | 33 (25.4) | 33 (80.5) | 0 (0) | <0.0001 |
Day of death | 15 (3–32) | 15 (3–32) | – | |
SAPS II | 33 (19–49) | 45 (35–72) | 24 (15–39) | <0.0001 |
UBS | 67 (24–146) | 110 (65–224) | 46 (16–113) | <0.0001 |
ABSI | 8 (6–10) | 11 (8–12) | 7 (5–9) | <0.0001 |
Serum creatinine on admission, μmol/L | 67 (65–113) | 88 (67–118) | 64 (54–77) | <0.0001 |
Maximal blood lactate concentration within 7 days, mmol/L | 4.3 (2.8–7) | 7 (5.2–9.4) | 3.2 (2.2–4.7) | <0.0001 |
Minimal serum haptoglobin level, g/L | 0.6 (0.1–1.2) | 0.1 (0.1–0.5) | 0.8 (0.5–1.4) | <0.0001 |
Undetectable haptoglobin level, n (%) | 39 (30) | 28 (68.3) | 11 (12.4) | <0.0001 |