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Table 1 Patient characteristics

From: Undetectable haptoglobin is associated with major adverse kidney events in critically ill burn patients

 

All patients (n = 130)

MAKE (n = 41)

No MAKE (n = 89)

p Value

Age, years

48.5 (34–61.8)

53 (47–67)

44 (29–58)

0.02

Sex, n (%)

 Male

80 (61.5)

24 (58.5)

56 (62.9)

0.7

 Female

50 (38.5)

17 (41.5)

33 (37.1)

BMI, kg/m2

25.1 (22.7–28.5)

26.2 (22.8–30.6)

24.9 (22.7–27.5)

0.06

Co-morbidities, n (%)

 Hypertension

27 (20.8)

13 (31.7)

14 (15.7)

0.06

 Diabetes mellitus

16 (12.3)

8 (19.5)

8 (9)

0.15

 Chronic kidney disease

2 (1.5)

1 (2.4)

1 (1.1)

0.53

 Vascular disease

8 (6.2)

3 (7.3)

5 (5.6)

0.71

 Obesity

21 (16.1)

12 (29.3)

9 (10.1)

0.01

 Smoking

14 (10.8)

2 (4.9)

12 (13.5)

0.22

 Alcohol consumption

15 (11.5)

5 (12.2)

10 (11.2)

1

 Psychiatric

17 (13.1)

6 (14.6)

11 (12.4)

0.78

Burn type, n (%)

 Thermal

123 (94.6)

41 (100)

82 (92.1)

0.1

 Electrical

7 (5.4)

0 (0)

7 (7.9)

Body surface area burned (%)

 Total

28.5 (15–50.8)

50 (22.5–70)

20 (12–40)

<0.0001

 Full thickness

15 (4–32.2)

25 (15–56)

8 (1.8–25)

<0.0001

ICU length of stay, days

27.5 (10–42.5)

18 (3–38)

29 (13.2–45)

0.42

Death in ICU, n (%)

33 (25.4)

33 (80.5)

0 (0)

<0.0001

 Day of death

15 (3–32)

15 (3–32)

SAPS II

33 (19–49)

45 (35–72)

24 (15–39)

<0.0001

UBS

67 (24–146)

110 (65–224)

46 (16–113)

<0.0001

ABSI

8 (6–10)

11 (8–12)

7 (5–9)

<0.0001

Serum creatinine on admission, μmol/L

67 (65–113)

88 (67–118)

64 (54–77)

<0.0001

Maximal blood lactate concentration within 7 days, mmol/L

4.3 (2.8–7)

7 (5.2–9.4)

3.2 (2.2–4.7)

<0.0001

Minimal serum haptoglobin level, g/L

0.6 (0.1–1.2)

0.1 (0.1–0.5)

0.8 (0.5–1.4)

<0.0001

Undetectable haptoglobin level, n (%)

39 (30)

28 (68.3)

11 (12.4)

<0.0001

  1. Abbreviations: BMI Body Mass Index, ICU Intensive Care Unit, SAPS II Simplified Acute Physiology Score II, UBS Unit Burn Standard, ABSI Abbreviated Burn Severity Index
  2. Data are expressed as median ± 25th–75th interquartile range for continuous variables and count (percent) for discrete variables