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Fig. 4 | Critical Care

Fig. 4

From: Systemic impact on secondary brain aggravation due to ischemia/reperfusion injury in post-cardiac arrest syndrome: a prospective observational study using high-mobility group box 1 protein

Fig. 4

Scatterplot showing the correlation between high-mobility group box 1 protein (HMGB1) and neuron-specific enolase (NSE) or interleukin (IL)-6 in the poor outcome group. Spearman’s rank correlation test was performed to analyze the correlation between HMGB1 and NSE or IL-6 in the poor outcome group. Correlation between HMGB1 and NSE at return of spontaneous circulation (ROSC) (a) and 24 h after ROSC (b) is represented on a logarithmic scale. Correlation between HMGB1 and IL-6 at ROSC (c) and 24 h after ROSC (d) is represented on a logarithmic scale. The measurement points at ROSC and 24 h are represented as 0 h and 24 h, respectively, in this graph. The coefficient of correlation is shown by ρ, and p < 0.05 is defined as statistically significant above the scatterplot. The reference line indicates positive correlation. The numbers of patients represented in the graphs are n = 103 (a), n = 89 (b), n = 103 (c), and n = 89 (d)

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Critical Care

ISSN: 1364-8535