Fig. 1From: Evaluating physical functioning in critical care: considerations for clinical practice and researchImpact of pre-ICU, critical illness and hospital/ICU factors on body systems related to physical functioning. Pre-ICU, critical illness, environmental factors, and body-system impairments, have interdependent effects on physical functioning (e.g., ICU culture regarding sedation may lead to neurological impairment resulting in immobility and musculoskeletal impairment)Back to article page