From: Loxapine to control agitation during weaning from mechanical ventilation
Loxapine | Placebo | p Value | |
---|---|---|---|
Ventilator-free days in first 14 days (SD) | 5.8 (8.4) | 5.5 (8.4) | 0.9 |
Unplanned extubations, n (%) | 6 (13) | 7 (18) | 0.5 |
Sedation resumption during the first 24 h, n (%) | 8 (17) | 17 (44) | 0.01 |
Nosocomial pneumonia, n (%) | 7 (15) | 8 (21) | 0.5 |
Mortality at 14 days, n (%) | 1 (2) | 2 (5) | 0.6 |
Mortality at 6 weeks, n (%) | 5 (10) | 3 (8) | 0.7 |