Table 3 Studies on primary FMT in nonrecurring CDI

Agraval et al., 2015 [80]

146 total

(57 with severe or complicated CDI)

?

82.9% primary

95.9% overall

All patients 65 years and older

Varying protocol for FMT

Aroniadis et al., 2015 [81]

17 with severe or complicated CDI

?

88.2% primary

94.1% overall

Fisher et al., 2015 [82]

29

13

62% primary

93% overall

Treatment protocol with FMT (colonoscopy) and continued vancomycin

 Pecere et al., 2015 [83]

1

Altered protocol with FMT and fidaxomicin

Zainah et al., 2014 [84]

14 with severe CDI

6

79%

FMT via NGT

Lagier et al., 2015 [59]

61 patients with CDI (O27)

?

81.25%

(vs 35.6%)

42 patients treated with antibiotics

3 patients treated with “tardive” FMT

16 patients treated with antibiotics and early FMT

Kelly et al., 2014 [85]

80 total

(34% severe CDI)

?

78% primary

89% overall

Study on immunocompromised patients; disease flares in 14% of patients with inflammatory bowel disease

Gweon et al., 2016 [86]

7 total

(2 with severe CDI)

?

100% overall

Study on older, multimorbid patients with primary FMT (administered orally)