Table 4 Logistic regression analysis for determining predictors of acute kidney injury in sepsis
From: Markers of acute kidney injury in patients with sepsis: the role of soluble thrombomodulin
| Â | OR (95% CI) (unadjusted) | P-value | OR (95% CI) (adjusted: model 1) | P value | OR (95% CI) (adjusted: model 2) | P value |
|---|---|---|---|---|---|---|
Coagulation biomarkers | ||||||
 Platelet | 1.00 (0.99–1.00) | <0.0001 | – | – | – | – |
 FDP | 1.01 (1.00–1.02) | 0.022 | – | – | – | – |
 PT | 0.98 (0.97–0.99) | <0.0001 | – | – | – | – |
 Fib | 1.00 (1.00–1.00) | 0.077 | – | – | – | – |
 α2-PI | 0.99 (0.99–1.00) | 0.029 | – | – | – | – |
 AT III | 0.98 (0.97–0.99) | <0.0001 | – | – | – | – |
 Plasminogen | 0.99 (0.98–0.99) | 0.0003 | – | – | – | – |
 TAT | 1.02 (1.01–1.04) | 0.0004 | – | – | – | – |
 PIC | 1.02 (0.95–1.11) | 0.603 | – | – | – | – |
 Overt DIC | 4.10 (2.39–7.47) | <0.0001 | – | – | – | – |
Endothelial activation | ||||||
 Protein C | 0.98 (0.98–0.99) | <0.0001 | – | – | – | – |
 sTM | 1.11 (1.06–1.17) | <0.0001 | 1.10 (1.04–1.16) | 0.001 | 1.09 (1.03–1.16) | 0.004 |
 E-selectin | 1.01 (1.00–1.02) | 0.029 | – | – | – | – |
 PAI-1 | 1.00 (1.00–1.00) | 0.007 | – | – | – | – |