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Table 3 AUROCs for predictors of acute kidney injury in sepsis

From: Markers of acute kidney injury in patients with sepsis: the role of soluble thrombomodulin

 

AUROC (95% CI)

Coagulation biomarkers

 Platelet

0.627 (0.576–0.675)

 FDP

0.614 (0.562–0.663)

 PT

0.629 (0.576–0.680)

 Fib

0.549 (0.494–0.602)

 α2-PI

0.564 (0.509–0.618)

 AT III

0.618 (0.564–0.670)

 Plasminogen

0.600 (0.545–0.652)

 TAT

0.591 (0.538–0.642)

 PIC

0.527 (0.475–0.579)

 Overt DIC

0.607 (0.572–0.641)

Endothelial activation

 Protein C

0.634 (0.581–0.685)

 sTM

0.758 (0.677–0.825)

 E-selectin

0.629 (0.492–0.748)

 PAI-1

0.669 (0.566–0.758)

  1. Abbreviations: AKI Acute kidney injury, AT III Antithrombin III, DIC Disseminated intravascular coagulation, FDP Fibrin degradation product, PAI-1 Plasminogen activator inhibitor-1, α 2 PI α2-Plasminogen inhibitor, PIC Plasmin-α2-plasmin inhibitor complex, PT Prothrombin time, sTM Soluble thrombomodulin, TAT Thrombin-antithrombin complex