From: Markers of acute kidney injury in patients with sepsis: the role of soluble thrombomodulin
 | All (n = 514) | AKI (n = 163) | Non-AKI (n = 351) | P value |
---|---|---|---|---|
Age, years | 69 (59–78) | 65 (56–74) | 71 (61–79) | 0.0003 |
BW, kg | 56.7 (48–66) | 55 (46–64) | 57 (49–67) | 0.336 |
Height, cm | 159 (151–166) | 159 (152–166) | 160 (150–166) | 0.823 |
Male sex | 53.9% | 53.4% | 54.1% | 0.873 |
APACHE II | 24 (18–30) | 19 (15–25) | 26 (20–31) | <0.0001 |
CKD | 28.0% | 21.5% | 31.1% | 0.032 |
Premorbid creatinine, μmol/L | 66.3 (53.0–84.9) | 61.9 (47.7–80.0) | 70.3 (53.9–89.5) | 0.007 |
 Premorbid creatinine, mg/dl | 0.75 (0.60–0.96) | 0.70 (0.54–0.91) | 0.80 (0.0.61–1.01) | 0.007 |
Baseline creatinine, μmol/L | 54.8 (50.9–71.6) | 55.1 (51.3–65.4) | 54.8 (50.8–72.5) | 0.011 |
 Baseline creatinine, mg/dl | 0.62 (0.58–0.81) | 0.62 (0.58–0.74) | 0.62 (0.57–0.82) | 0.011 |
Hypertension | 48.8% | 39.3% | 53.3% | 0.003 |
IHD | 8.8% | 5.5% | 10.3% | 0.077 |
CHF | 8.8% | 4.9% | 10.5% | 0.036 |
COPD | 5.1% | 7.4% | 4.0% | 0.104 |
CVA | 11.1% | 8.6% | 12.3% | 0.219 |
DM | 25.7% | 21.5% | 27.6% | 0.137 |
Immunocompromised | 29.2% | 27.6% | 29.9% | 0.592 |
Infection site | Â | Â | Â | 0.013 |
 Intracranial | 1.2% | 2.5% | 0.6% |  |
 Head and neck | 5.5% | 9.2% | 3.7% |  |
 Thoracic | 22.4% | 22.1% | 22.5% |  |
 Abdominal | 50.8% | 53.4% | 49.6% |  |
 Soft tissue | 6.0% | 4.9% | 6.6% |  |
 CR-BSI | 1.0% | 0.0% | 1.4% |  |
 UTI | 5.3% | 3.7% | 6.0% |  |
 Others | 8.0% | 4.3% | 10.3% |  |
Mechanical ventilation | 82.9% | 76.7% | 85.8% | 0.011 |
28-day mortality | 11.7% | 3.1% | 15.6% | <0.0001 |
90-day mortality | 19.3% | 8.4% | 24.5% | <0.0001 |