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Fig. 1 | Critical Care

Fig. 1

From: Hyperfibrinolysis in severe isolated traumatic brain injury may occur without tissue hypoperfusion: a retrospective observational multicentre study

Fig. 1

Flow chart of the selection of patients in the traumatic brain injury (TBI) and non-TBI groups. The Japanese Observational Study for Coagulation and Thrombolysis in Early Trauma (J-OCTET) recruited 796 patients with severe trauma with an injury severity score ≥ 16, who were admitted to the emergency department (ED). Patients with isolated severe TBI were defined as patients with an abbreviated injury score (AIS) for the head ≥ 4 and an extra-cranial AIS < 2. Patients with severe extra-cranial trauma without TBI (non-TBI patients) were defined by an extra-cranial AIS ≥ 3 and head AIS < 2. Patients were excluded if they had used anti-coagulant or anti-platelet drugs before the accident or received an infusion before arrival at the ED. Patients with penetrating trauma and those whose D-dimer levels were not measured on arrival at the ED were also excluded

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Critical Care

ISSN: 1364-8535