Disseminated intravascular coagulation with increased fibrinolysis during the early phase of isolated traumatic brain injury

Table 2 Demographic and clinical characteristics of the DIC patients

	DIC
	Hyperfibrinolysis no	Hyperfibrinolysis yes	p value
	(n = 28)	(n = 17)
Age (years)	45 (22–65)	66 (52–77)	0.008
Male sex	21 (75.0)	9 (52.9)	0.193
Brain injury	18 (64.2)	12 (70.6)	0.752
JAAM DIC score	4 (4–4.8)	5 (5–7)	0.000
ISTH DIC score	3 (3–3)	4 (3–5)	0.002
ISTH DIC	1 (3.6)	6 (35.3)	0.008
APACHE II score	20 (15–27)	28 (20–35)	0.040
Injury Severity Score	24 (18–26)	25 (21–28)	0.396
SIRS score	4 (3–4)	4 (3–4)	0.957
SOFA score	5 (4–6.8)	6 (5–7.5)	0.083
Transfusion
Red blood cell concentrate (ml)	0 (0–192)	240 (140–540)	0.008
Fresh frozen plasma (ml)	0 (0–150)	120 (0–384)	0.127
Platelet concentrate (U)	0 (0–0)	0 (0–3.8)	0.118
Outcome death	3 (10.7)	10 (58.9)	0.001

Data presented as median (interquartile range) or n (%)
DIC disseminated intravascular coagulation, JAAM Japanese Association for Acute Medicine, ISTH International Society on Thrombosis and Haemostasis, APACHE Acute Physiology and Chronic Health Evaluation, SIRS systemic inflammatory response syndrome, SOFA Sequential Organ Failure Assessment

ISSN: 1364-8535