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Table 1 Demographic and clinical characteristics of the whole study population

From: Disseminated intravascular coagulation with increased fibrinolysis during the early phase of isolated traumatic brain injury

 

No DIC

DIC

p value

(47)

(45)

 

Age (years)

49 (31–64)

56 (36–70)

0.261

Male sex

37 (78.7)

30 (66.7)

0.244

Time from call receipt to arrival at ED

31.0 (22.8–43.0)

31.5 (24.0–37.0)

0.799

JAAM DIC score

1 (1–2)

4 (4–6)

0.000

ISTH DIC score

1 (0–2)

3 (3–4)

0.000

ISTH DIC

0 (0)

7 (15.6)

0.000

Hyperfibrinolysis

0 (0)

17 (37.8)

0.000

APACHE II score

18 (11–27)

24.0 (18–31)

0.028

Injury Severity Score

24 (17–26)

24.0 (19–26)

0.330

Abbreviated Injury Scale

 Head and neck

4 (4–5)

4 (4–5)

0.154

 Face

2 (2–3)

2 (2–2)

0.309

 Chest

2 (1–2)

1 (1–1)

0.282

 Abdomen

2 (2–2)

2 (2–2)

0.825

 Extremity

2 (1–2)

2 (1–2)

0.934

 External

1 (1–2)

1 (1–1)

0.281

SIRS score

3 (3–3)

4 (3–4)

0.000

SIRS

44 (93.6)

45 (100)

0.215

SOFA score

4 (3–5)

5 (4–7)

0.000

Mean blood pressure (mmHg)

90 (80–109)

91 (76–112)

0.821

Catecholamine (n,%)

1 (2.1)

4 (8.9)

0.198

Hypoperfusion

11 (23.4)

29 (64.4)

0.000

Lactate (mmol/L)

2.9 (2.1–4.0)

4.6 (3.6–7.0)

0.000

Transfusion

 Red blood cell concentrate (ml)

0 (0–0)

140 (0–390)

0.000

 Fresh frozen plasma (ml)

0 (0–0)

0 (0–240)

0.000

 Platelet concentrate (U)

0 (0–0)

0 (0–0)

0.995

Tranexamic acid (n,%)

5 (10.6)

13 (28.9)

0.025

Outcome death

5 (10.6)

13 (28.9)

0.025

  1. Data presented as median (interquartile range) or n (%)
  2. DIC disseminated intravascular coagulation, ED emergency department, JAAM Japanese Association for Acute Medicine, ISTH International Society on Thrombosis and Haemostasis, APACHE Acute Physiology and Chronic Health Evaluation, SIRS systemic inflammatory response syndrome, SOFA Sequential Organ Failure Assessment