Incidence, prevalence, and management of MRSA bacteremia across patient populations—a review of recent developments in MRSA management and treatment

Table 1 Sensitivity and specificity of different MRSA testing methodologies based on pooled data

MRSA testing modality	Number of studies	Sensitivity, % (95% CI)	Specificity, % (95% CI)
Culture 48 h	7	86.9 (74.7–93.7)	89.7 (77.7–95.6)^a
Chromogenic media, 18–24 h	28	78.3 (71.0–84.1)^a,b	98.6 (97.7–99.1)^b,c
Chromogenic media, 48 h	24	87.6 (82.1–91.6)	94.7 (91.6–96.8)
PCR	15	92.5 (87.4–95.9)	97.0 (94.5–98.4)

Adapted from data presented in Luteijn et al. [53]
Abbreviations: CI confidence interval, MRSA methicillin-resistant S. aureus, PCR polymerase chain reaction
^a P <0.05 vs PCR
^b P <0.05 vs chromogenic media at 48 h
^c P < 0.05 vs culture at 48 h

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