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Fig. 2 | Critical Care

Fig. 2

From: Inhaled AP301 for treatment of pulmonary edema in mechanically ventilated patients with acute respiratory distress syndrome: a phase IIa randomized placebo-controlled trial

Fig. 2

Baseline-adjusted differences in extravascular lung water index (EVLWI) over 7 days. Comparison of 7-day (d0–d7) treatment with inhaled AP301 (dashed line) or placebo (dotted line). Data are given as mean and patient count per day. A positive ΔEVLWI indicates a decrease from baseline value at screening. a AP301 versus placebo. b AP301 versus placebo in stratum A (SOFA score ≤10). c AP301 versus placebo in stratum B (SOFA score ≥11). *p = 0.04. ns not significant, PBW predicted body weight

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Critical Care

ISSN: 1364-8535