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Fig. 3 | Critical Care

Fig. 3

From: Costs and expected gain in lifetime health from intensive care versus general ward care of 30,712 individual patients: a distribution-weighted cost-effectiveness analysis

Fig. 3

a Individualized cost-effectiveness with and without distribution weights for severity of disease: the disaggregated individual results. Each line is made up of 30,712 points. Each point represents the ICER for an individual admission. The individualized ICERs are sorted from the lowest (left) to the highest (right) ICER. There was a 50% probability (median, black line) that ICU admission was cost-effective for 85% of the patients at a threshold of €64,000/QALY (long dashed line). The figure illustrates that after assigning distribution weights according to severity of disease, i.e. higher weights to the health gains of patients with fewer lifetime QALYs if rejected, ICU admission can be considered acceptable for more patients (thick grey line) for any cost-effectiveness threshold compared to the standard analysis (black line). b Individualized cost-effectiveness in subgroups by type of admission. The individualized incremental cost-effectiveness ratios were plotted as points forming a line. The individualized ICERs are sorted from the lowest (left) to the highest (right) ICER. The thick black line is the median result for each individual from 1000 replications of the model. The long dashed line indicates a general cost-effectiveness threshold of €64,000/QALY. ICER incremental cost-effectiveness ratio, QALY quality-adjusted life year

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